SF-Cluster Copyright (c) 2026 Hanqun Cao This software builds on the following third-party work, which it depends on at runtime but does NOT redistribute. Each retains its own license and authorship. 1. FrustrAI-Seq — per-residue frustration prediction model. License: Apache-2.0. Source: https://github.com/leuschjanphilipp/FrustrAI-Seq Weights: https://huggingface.co/leuschj/FrustrAI-Seq SF-Cluster calls this model to compute the frustration features that guide MSA subsampling. Install and weights are fetched from the upstream sources. 2. ProtT5 (Rostlab/prot_t5_xl_half_uniref50-enc) — protein language model used internally by FrustrAI-Seq. Source: https://huggingface.co/Rostlab/prot_t5_xl_half_uniref50-enc 3. AF-Cluster (Wayment-Steele et al.) — the MSA-clustering method SF-Cluster is compared against and conceptually extends. License: MIT. Source: https://github.com/HWaymentSteele/AF_Cluster AlphaFold2 / ColabFold are used as the downstream structure predictor and are neither included nor wrapped by this package; install them separately under their own licenses.