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Datasets:
Innovative-Process-Applications
/
ipa-pharma-compactor-platform

Tasks:
Tabular Regression
Modalities:
Tabular
Text
Formats:
csv
Languages:
English
Size:
1K - 10K
Tags:
roller-compaction
pharmaceutical-manufacturing
dry-granulation
scale-up
quality-by-design
twin-feed-screw
Libraries:
Datasets
pandas
Polars
License:
Dataset card Data Studio Files
xet
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1
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run_id
int64
1
3k
compactor_model
stringclasses
5 values
scale
stringclasses
5 values
roll_diameter_in
float64
1
4
roll_width_in
int64
6
10
roll_diameter_cm
float64
2.5
10
roll_width_cm
int64
15
25
max_roll_pressure_kn_cm
float64
15
26
integrated_mill
stringclasses
3 values
total_power_kw
float64
2
19
material
stringclasses
5 values
feed_density_gcc
float64
0.32
0.62
deformation_type
stringclasses
3 values
roll_pressure_fraction
float64
0.3
1
scf_kn_cm
float64
0.52
3.24
roll_speed_rpm
int64
2
10
hfs_speed_rpm
int64
15
100
vfs_hfs_ratio
float64
0.6
1.5
gap_width_mm
float64
1.2
1.8
ribbon_rel_density
float64
0.35
0.79
ribbon_density_gcc
float64
0.46
0.99
ribbon_porosity
float64
0.21
0.65
density_cv_pct
float64
2.16
10.4
fines_pct
float64
11.7
41.8
granule_yield_pct
float64
56.5
89
in_zinchuk_window
stringclasses
2 values
throughput_kg_hr
float64
4.4
445
throughput_lbs_hr
float64
9.8
981
specific_energy_kwh_tonne
float64
18.3
847
changeover_time_hr
float64
1
2.5
replicate
int64
1
3
1
CL100250
Full Production
4
10
10
25
17.5
PM8
19
API_blend_40pct
0.38
mixed
0.7
1.21
10
100
0.6
1.23
0.4508
0.586
0.5492
4.1
30.3
71.83
No
196.2
432.5
79.41
2.5
1
2
CL100250
Full Production
4
10
10
25
17.5
PM8
19
API_blend_40pct
0.38
mixed
1
1.73
6
15
1
1.57
0.5015
0.6519
0.4985
4.21
26.49
72.55
No
114.6
252.7
165.77
2.5
1
3
CL100250
Full Production
4
10
10
25
17.5
PM8
19
API_blend_40pct
0.38
mixed
0.5
0.87
4
75
0.6
1.73
0.4197
0.5456
0.5803
5.29
31.4
69.55
No
141.5
311.9
94.01
2.5
1
4
CL100250
Full Production
4
10
10
25
17.5
PM8
19
API_blend_40pct
0.38
mixed
0.7
1.21
2
75
1.2
1.44
0.4503
0.5854
0.5497
8.05
31.33
68.81
No
127.9
282
121.79
2.5
3
5
CL100250
Full Production
4
10
10
25
17.5
PM8
19
API_blend_40pct
0.38
mixed
1
1.73
10
75
1.2
1.77
0.4872
0.6333
0.5128
3.99
29.46
71.21
No
186.8
411.9
101.7
2.5
3
6
CL100250
Full Production
4
10
10
25
17.5
PM8
19
API_blend_40pct
0.38
mixed
0.85
1.47
10
30
1
1.58
0.4904
0.6376
0.5096
4.38
29.63
69.18
No
157.2
346.5
110
2.5
1
7
CL100250
Full Production
4
10
10
25
17.5
PM8
19
API_blend_40pct
0.38
mixed
1
1.73
6
15
1.2
1.28
0.4835
0.6285
0.5165
5.23
27.65
73.36
No
113.8
250.9
166.97
2.5
2
8
CL100250
Full Production
4
10
10
25
17.5
PM8
19
API_blend_40pct
0.38
mixed
0.3
0.52
10
30
0.6
1.23
0.3867
0.5027
0.6133
5.02
35.81
63.31
No
155.4
342.5
70.93
2.5
2
9
CL100250
Full Production
4
10
10
25
17.5
PM8
19
API_blend_40pct
0.38
mixed
0.5
0.87
2
75
1
1.71
0.4321
0.5617
0.5679
7.12
32.85
68.42
No
129.4
285.4
102.75
2.5
2
10
CL100250
Full Production
4
10
10
25
17.5
PM8
19
API_blend_40pct
0.38
mixed
0.85
1.47
6
50
0.6
1.43
0.4512
0.5865
0.5488
4.13
30.41
68.37
No
133.5
294.3
129.52
2.5
3
11
CL100250
Full Production
4
10
10
25
17.5
PM8
19
API_blend_40pct
0.38
mixed
0.5
0.87
8
75
1
1.69
0.4571
0.5943
0.5429
3.51
28.36
70.77
No
163.7
361
81.23
2.5
1
12
CL100250
Full Production
4
10
10
25
17.5
PM8
19
API_blend_40pct
0.38
mixed
0.7
1.21
2
100
1
1.76
0.4439
0.5771
0.5561
8.74
30.58
68.47
No
149.8
330.3
104
2.5
3
13
CL100250
Full Production
4
10
10
25
17.5
PM8
19
API_blend_40pct
0.38
mixed
0.3
0.52
10
15
0.8
1.61
0.4084
0.531
0.5916
4.83
33.5
66.88
No
150.6
332
73.18
2.5
1
14
CL100250
Full Production
4
10
10
25
17.5
PM8
19
API_blend_40pct
0.38
mixed
1
1.73
8
15
1
1.47
0.5119
0.6654
0.4881
4.52
25.83
74.35
No
137
301.9
138.74
2.5
2
15
CL100250
Full Production
4
10
10
25
17.5
PM8
19
API_blend_40pct
0.38
mixed
0.5
0.87
4
100
0.8
1.32
0.4131
0.537
0.5869
5.76
32.42
68.06
No
160.3
353.3
82.98
2.5
2
16
CL100250
Full Production
4
10
10
25
17.5
PM8
19
API_blend_40pct
0.38
mixed
0.7
1.21
6
15
0.8
1.69
0.4481
0.5825
0.5519
4.96
32.63
66.32
No
117.3
258.7
132.79
2.5
3
17
CL100250
Full Production
4
10
10
25
17.5
PM8
19
API_blend_40pct
0.38
mixed
0.7
1.21
4
75
1.2
1.7
0.4525
0.5882
0.5475
5.17
28.44
71.99
No
141.5
311.9
110.12
2.5
3
18
CL100250
Full Production
4
10
10
25
17.5
PM8
19
API_blend_40pct
0.38
mixed
0.7
1.21
8
30
1.2
1.8
0.4357
0.5663
0.5643
4.75
29.66
70.12
No
139.6
307.7
111.63
2.5
3
19
CL100250
Full Production
4
10
10
25
17.5
PM8
19
API_blend_40pct
0.38
mixed
0.3
0.52
8
15
1
1.55
0.4062
0.5281
0.5938
4.21
33.7
64.29
No
129.8
286.1
84.91
2.5
1
20
CL100250
Full Production
4
10
10
25
17.5
PM8
19
API_blend_40pct
0.38
mixed
0.85
1.47
6
100
1
1.69
0.4834
0.6284
0.5166
4.38
27.64
73.36
No
176.8
389.7
97.82
2.5
1
21
CL100250
Full Production
4
10
10
25
17.5
PM8
19
API_blend_40pct
0.38
mixed
0.7
1.21
6
50
1.5
1.4
0.4518
0.5874
0.5482
4.43
30.42
71.14
No
138.1
304.5
112.8
2.5
3
22
CL100250
Full Production
4
10
10
25
17.5
PM8
19
API_blend_40pct
0.38
mixed
0.3
0.52
6
100
1
1.77
0.4093
0.5321
0.5907
3.84
32.07
67.77
No
173.4
382.3
63.54
2.5
3
23
CL100250
Full Production
4
10
10
25
17.5
PM8
19
API_blend_40pct
0.38
mixed
1
1.73
2
50
1
1.65
0.4826
0.6274
0.5174
5.84
30.02
69.55
No
114.3
252
166.19
2.5
3
24
CL100250
Full Production
4
10
10
25
17.5
PM8
19
API_blend_40pct
0.38
mixed
0.85
1.47
10
30
0.6
1.43
0.4375
0.5687
0.5625
4.77
27.69
72.55
No
150.6
332
114.83
2.5
2
25
CL100250
Full Production
4
10
10
25
17.5
PM8
19
API_blend_40pct
0.38
mixed
0.3
0.52
6
75
0.6
1.32
0.4001
0.5202
0.5999
4.54
33.92
68.44
No
153.9
339.3
71.6
2.5
2
26
CL100250
Full Production
4
10
10
25
17.5
PM8
19
API_blend_40pct
0.38
mixed
1
1.73
4
15
0.6
1.5
0.4739
0.616
0.5261
4.51
27.06
73.19
No
105.6
232.7
179.98
2.5
2
27
CL100250
Full Production
4
10
10
25
17.5
PM8
19
API_blend_40pct
0.38
mixed
1
1.73
8
15
1.5
1.22
0.47
0.6109
0.53
4.81
26.57
73.04
No
135.4
298.5
140.32
2.5
1
28
CL100250
Full Production
4
10
10
25
17.5
PM8
19
API_blend_40pct
0.38
mixed
0.5
0.87
6
100
0.8
1.34
0.43
0.559
0.57
4.74
34.39
65.35
No
173
381.4
76.88
2.5
3
29
CL100250
Full Production
4
10
10
25
17.5
PM8
19
API_blend_40pct
0.38
mixed
0.85
1.47
4
15
1
1.2
0.5012
0.6515
0.4988
4.3
25.72
73.9
No
100.2
220.8
172.6
2.5
3
30
CL100250
Full Production
4
10
10
25
17.5
PM8
19
API_blend_40pct
0.38
mixed
1
1.73
4
75
1.5
1.64
0.445
0.5785
0.555
5.13
31.09
70.05
No
142.9
315
132.99
2.5
2
31
CL100250
Full Production
4
10
10
25
17.5
PM8
19
API_blend_40pct
0.38
mixed
0.3
0.52
4
50
0.8
1.29
0.4276
0.5558
0.5724
3.74
33.43
66.88
No
132
290.9
83.51
2.5
2
32
CL100250
Full Production
4
10
10
25
17.5
PM8
19
API_blend_40pct
0.38
mixed
0.3
0.52
4
50
1
1.68
0.4524
0.5881
0.5476
3.39
30.91
68.7
No
126.5
278.9
87.09
2.5
1
33
CL100250
Full Production
4
10
10
25
17.5
PM8
19
API_blend_40pct
0.38
mixed
1
1.73
2
75
0.8
1.71
0.4549
0.5914
0.5451
7.73
30.64
69.42
No
130.7
288.1
145.37
2.5
3
34
CL100250
Full Production
4
10
10
25
17.5
PM8
19
API_blend_40pct
0.38
mixed
0.5
0.87
2
30
1
1.59
0.4485
0.5831
0.5515
3.72
29.78
70.88
No
99.2
218.7
134.07
2.5
3
35
CL100250
Full Production
4
10
10
25
17.5
PM8
19
API_blend_40pct
0.38
mixed
0.5
0.87
10
30
0.8
1.59
0.4172
0.5423
0.5828
5.14
31.58
68.15
No
156.1
344.1
85.21
2.5
2
36
CL100250
Full Production
4
10
10
25
17.5
PM8
19
API_blend_40pct
0.38
mixed
0.3
0.52
10
50
1.5
1.44
0.3706
0.4818
0.6294
4.79
34.68
67.03
No
175.8
387.5
62.7
2.5
1
37
CL100250
Full Production
4
10
10
25
17.5
PM8
19
API_blend_40pct
0.38
mixed
0.5
0.87
6
50
0.6
1.37
0.4116
0.535
0.5884
4.22
30.47
68.24
No
147.3
324.8
90.28
2.5
3
38
CL100250
Full Production
4
10
10
25
17.5
PM8
19
API_blend_40pct
0.38
mixed
0.5
0.87
2
75
0.6
1.28
0.4008
0.521
0.5992
8.14
31.17
70.07
No
127.2
280.4
104.55
2.5
1
39
CL100250
Full Production
4
10
10
25
17.5
PM8
19
API_blend_40pct
0.38
mixed
0.7
1.21
6
100
1
1.64
0.4673
0.6075
0.5327
3.93
29.38
71.2
No
178.8
394.1
87.14
2.5
3
40
CL100250
Full Production
4
10
10
25
17.5
PM8
19
API_blend_40pct
0.38
mixed
0.85
1.47
4
75
1
1.35
0.4947
0.6431
0.5053
4.82
26.61
74.47
No
142.1
313.2
121.71
2.5
2
41
CL100250
Full Production
4
10
10
25
17.5
PM8
19
API_blend_40pct
0.38
mixed
0.7
1.21
6
30
0.6
1.74
0.4319
0.5615
0.5681
5.15
30.61
69.32
No
128.3
282.8
121.46
2.5
2
42
CL100250
Full Production
4
10
10
25
17.5
PM8
19
API_blend_40pct
0.38
mixed
0.3
0.52
10
100
1
1.48
0.414
0.5381
0.586
3.28
29.43
71.51
No
197.9
436.3
55.68
2.5
2
43
CL100250
Full Production
4
10
10
25
17.5
PM8
19
API_blend_40pct
0.38
mixed
0.5
0.87
6
100
1.2
1.67
0.4251
0.5526
0.5749
4.87
31.45
67.34
No
178.6
393.8
74.45
2.5
3
44
CL100250
Full Production
4
10
10
25
17.5
PM8
19
API_blend_40pct
0.38
mixed
0.5
0.87
10
100
0.6
1.78
0.4143
0.5386
0.5857
2.95
30.82
70.31
No
189.8
418.4
70.09
2.5
2
45
CL100250
Full Production
4
10
10
25
17.5
PM8
19
API_blend_40pct
0.38
mixed
0.3
0.52
8
30
1.2
1.57
0.4166
0.5416
0.5834
4.66
33.9
65.17
No
146.3
322.5
75.33
2.5
3
46
CL100250
Full Production
4
10
10
25
17.5
PM8
19
API_blend_40pct
0.38
mixed
0.7
1.21
2
30
0.6
1.58
0.4385
0.5701
0.5615
5.14
29.59
70.32
No
100.6
221.7
154.91
2.5
1
47
CL100250
Full Production
4
10
10
25
17.5
PM8
19
API_blend_40pct
0.38
mixed
0.3
0.52
8
100
1.5
1.52
0.3809
0.4952
0.6191
4.71
35.53
64.13
No
172.5
380.4
63.87
2.5
2
48
CL100250
Full Production
4
10
10
25
17.5
PM8
19
API_blend_40pct
0.38
mixed
1
1.73
8
100
1.5
1.36
0.4891
0.6359
0.5109
4.75
28.66
69.55
No
181.5
400.2
104.66
2.5
1
49
CL100250
Full Production
4
10
10
25
17.5
PM8
19
API_blend_40pct
0.38
mixed
0.5
0.87
2
100
0.8
1.75
0.4259
0.5536
0.5741
9.5
32.26
68.58
No
146.7
323.5
90.63
2.5
2
50
CL100250
Full Production
4
10
10
25
17.5
PM8
19
API_blend_40pct
0.38
mixed
0.5
0.87
2
50
1.2
1.32
0.433
0.5629
0.567
5.44
31.75
67.77
No
115.9
255.5
114.77
2.5
3
51
CL100250
Full Production
4
10
10
25
17.5
PM8
19
API_blend_40pct
0.38
mixed
0.5
0.87
4
50
1.5
1.23
0.4102
0.5332
0.5898
4.2
34.81
65.14
No
129.2
284.9
102.92
2.5
3
52
CL100250
Full Production
4
10
10
25
17.5
PM8
19
API_blend_40pct
0.38
mixed
1
1.73
10
15
1.2
1.27
0.4912
0.6386
0.5088
5.35
27.05
72.68
No
139.1
306.7
136.56
2.5
3
53
CL100250
Full Production
4
10
10
25
17.5
PM8
19
API_blend_40pct
0.38
mixed
0.85
1.47
6
50
1.2
1.67
0.4679
0.6083
0.5321
4.22
28.57
70.39
No
140.9
310.6
122.73
2.5
1
54
CL100250
Full Production
4
10
10
25
17.5
PM8
19
API_blend_40pct
0.38
mixed
0.85
1.47
8
50
0.8
1.32
0.4713
0.6127
0.5287
4.4
28.07
71.14
No
154.5
340.6
111.92
2.5
1
55
CL100250
Full Production
4
10
10
25
17.5
PM8
19
API_blend_40pct
0.38
mixed
0.85
1.47
2
50
1
1.5
0.463
0.602
0.537
4.91
28.22
71.49
No
112.7
248.5
153.38
2.5
3
56
CL100250
Full Production
4
10
10
25
17.5
PM8
19
API_blend_40pct
0.38
mixed
0.5
0.87
4
100
1
1.4
0.4522
0.5878
0.5478
5.2
30.46
71.52
No
151.8
334.6
87.63
2.5
3
57
CL100250
Full Production
4
10
10
25
17.5
PM8
19
API_blend_40pct
0.38
mixed
0.85
1.47
2
100
1
1.8
0.4897
0.6365
0.5103
9.18
26.88
74.06
No
144.9
319.5
119.31
2.5
2
58
CL100250
Full Production
4
10
10
25
17.5
PM8
19
API_blend_40pct
0.38
mixed
1
1.73
6
75
1.5
1.21
0.4784
0.6219
0.5216
4.49
27.72
73
No
151.6
334.1
125.36
2.5
1
59
CL100250
Full Production
4
10
10
25
17.5
PM8
19
API_blend_40pct
0.38
mixed
0.3
0.52
10
75
0.8
1.59
0.3924
0.5101
0.6076
3.73
33.6
67.17
No
175.7
387.3
62.73
2.5
3
60
CL100250
Full Production
4
10
10
25
17.5
PM8
19
API_blend_40pct
0.38
mixed
0.85
1.47
6
50
0.8
1.74
0.4624
0.6011
0.5376
3.79
31.6
66.58
No
143.7
316.7
120.36
2.5
2
61
CL100250
Full Production
4
10
10
25
17.5
PM8
19
API_blend_40pct
0.38
mixed
1
1.73
6
75
1.2
1.43
0.5064
0.6583
0.4936
4.02
29.13
69.84
No
153.9
339.4
123.43
2.5
3
62
CL100250
Full Production
4
10
10
25
17.5
PM8
19
API_blend_40pct
0.38
mixed
0.5
0.87
4
50
0.6
1.44
0.4357
0.5665
0.5643
4.48
31.26
69.97
No
127.3
280.6
104.5
2.5
1
63
CL100250
Full Production
4
10
10
25
17.5
PM8
19
API_blend_40pct
0.38
mixed
0.7
1.21
10
15
0.6
1.51
0.4348
0.5652
0.5652
5.02
29.51
70.19
No
147.2
324.5
105.84
2.5
1
64
CL100250
Full Production
4
10
10
25
17.5
PM8
19
API_blend_40pct
0.38
mixed
0.5
0.87
8
100
1.2
1.4
0.4419
0.5744
0.5581
3.78
29.91
67.28
No
196.2
432.6
67.78
2.5
1
65
CL100250
Full Production
4
10
10
25
17.5
PM8
19
API_blend_40pct
0.38
mixed
0.7
1.21
2
50
1
1.23
0.4673
0.6075
0.5327
5.79
28.1
71.24
No
118.7
261.6
131.29
2.5
3
66
CL100250
Full Production
4
10
10
25
17.5
PM8
19
API_blend_40pct
0.38
mixed
0.3
0.52
2
100
0.8
1.77
0.4034
0.5244
0.5966
9.54
33.16
66.92
No
152.9
337
72.09
2.5
3
67
CL100250
Full Production
4
10
10
25
17.5
PM8
19
API_blend_40pct
0.38
mixed
0.85
1.47
10
15
1.2
1.62
0.4381
0.5696
0.5619
4.44
31.19
68.49
No
147
324.1
117.6
2.5
3
68
CL100250
Full Production
4
10
10
25
17.5
PM8
19
API_blend_40pct
0.38
mixed
1
1.73
6
30
0.8
1.61
0.4903
0.6374
0.5097
4.55
30.1
69.08
No
126.9
279.8
149.68
2.5
1
69
CL100250
Full Production
4
10
10
25
17.5
PM8
19
API_blend_40pct
0.38
mixed
0.7
1.21
6
30
1.2
1.58
0.4487
0.5833
0.5513
4.32
31.66
67.81
No
126.8
279.5
122.87
2.5
2
70
CL100250
Full Production
4
10
10
25
17.5
PM8
19
API_blend_40pct
0.38
mixed
0.3
0.52
2
30
1.5
1.76
0.3951
0.5136
0.6049
4.89
32.46
66.62
No
97.7
215.4
112.77
2.5
3
71
CL100250
Full Production
4
10
10
25
17.5
PM8
19
API_blend_40pct
0.38
mixed
0.3
0.52
10
100
1.5
1.74
0.4074
0.5296
0.5926
3.47
32.95
67.11
No
202
445.3
54.56
2.5
3
72
CL100250
Full Production
4
10
10
25
17.5
PM8
19
API_blend_40pct
0.38
mixed
0.5
0.87
2
75
1.5
1.44
0.4078
0.5301
0.5922
8.22
31.12
68.97
No
129.7
285.9
102.55
2.5
2
73
CL100250
Full Production
4
10
10
25
17.5
PM8
19
API_blend_40pct
0.38
mixed
0.5
0.87
4
15
1.5
1.76
0.4142
0.5385
0.5858
5.12
32.26
67.24
No
103.5
228.1
128.55
2.5
3
74
CL100250
Full Production
4
10
10
25
17.5
PM8
19
API_blend_40pct
0.38
mixed
0.7
1.21
4
100
0.6
1.66
0.4101
0.5332
0.5899
6.8
33.14
66.09
No
151.9
334.9
102.57
2.5
2
75
CL100250
Full Production
4
10
10
25
17.5
PM8
19
API_blend_40pct
0.38
mixed
0.3
0.52
10
30
1
1.2
0.4208
0.5471
0.5792
4.35
32.5
66.96
No
160.2
353.2
68.78
2.5
2
76
CL100250
Full Production
4
10
10
25
17.5
PM8
19
API_blend_40pct
0.38
mixed
0.5
0.87
6
15
1.5
1.23
0.406
0.5279
0.594
5.52
31.69
69.07
No
114.3
251.9
116.39
2.5
2
77
CL100250
Full Production
4
10
10
25
17.5
PM8
19
API_blend_40pct
0.38
mixed
0.85
1.47
6
100
0.8
1.27
0.4871
0.6333
0.5129
4.38
28.2
73.7
No
168.6
371.8
102.52
2.5
3
78
CL100250
Full Production
4
10
10
25
17.5
PM8
19
API_blend_40pct
0.38
mixed
0.3
0.52
10
30
1.2
1.49
0.3904
0.5075
0.6096
4.44
36.64
63.36
No
164.3
362.2
67.08
2.5
1
79
CL100250
Full Production
4
10
10
25
17.5
PM8
19
API_blend_40pct
0.38
mixed
0.85
1.47
6
75
0.8
1.32
0.484
0.6292
0.516
4.12
27.52
72.7
No
165
363.7
104.81
2.5
3
80
CL100250
Full Production
4
10
10
25
17.5
PM8
19
API_blend_40pct
0.38
mixed
1
1.73
4
75
1
1.56
0.488
0.6344
0.512
4.53
28.88
69.79
No
136.8
301.7
138.84
2.5
2
81
CL100250
Full Production
4
10
10
25
17.5
PM8
19
API_blend_40pct
0.38
mixed
0.5
0.87
6
100
1
1.49
0.4556
0.5923
0.5444
3.8
28.96
68.86
No
179.2
395.1
74.22
2.5
1
82
CL100250
Full Production
4
10
10
25
17.5
PM8
19
API_blend_40pct
0.38
mixed
0.85
1.47
4
100
0.8
1.47
0.4566
0.5936
0.5434
5.5
29.82
68.92
No
173.2
381.9
99.81
2.5
1
83
CL100250
Full Production
4
10
10
25
17.5
PM8
19
API_blend_40pct
0.38
mixed
0.5
0.87
4
30
1.5
1.78
0.4146
0.5389
0.5854
4.24
31.06
68.6
No
115.6
254.9
115.02
2.5
3
84
CL100250
Full Production
4
10
10
25
17.5
PM8
19
API_blend_40pct
0.38
mixed
0.7
1.21
6
30
1
1.34
0.4985
0.6481
0.5015
3.77
28.59
72.38
No
134.8
297.2
115.58
2.5
2
85
CL100250
Full Production
4
10
10
25
17.5
PM8
19
API_blend_40pct
0.38
mixed
0.5
0.87
8
15
1.2
1.52
0.445
0.5786
0.555
5.22
30.78
68.12
No
132.3
291.7
100.52
2.5
1
86
CL100250
Full Production
4
10
10
25
17.5
PM8
19
API_blend_40pct
0.38
mixed
0.85
1.47
8
15
1
1.55
0.4904
0.6376
0.5096
4.77
26.3
73.6
No
135.5
298.7
127.6
2.5
2
87
CL100250
Full Production
4
10
10
25
17.5
PM8
19
API_blend_40pct
0.38
mixed
0.7
1.21
4
50
0.6
1.67
0.4328
0.5626
0.5672
4.54
29.42
71.34
No
127.1
280.3
122.54
2.5
1
88
CL100250
Full Production
4
10
10
25
17.5
PM8
19
API_blend_40pct
0.38
mixed
1
1.73
8
100
0.8
1.54
0.4816
0.626
0.5184
3.65
28.74
72.76
No
169.2
373
112.3
2.5
2
89
CL100250
Full Production
4
10
10
25
17.5
PM8
19
API_blend_40pct
0.38
mixed
0.5
0.87
2
50
0.8
1.76
0.4235
0.5505
0.5765
5.9
31.3
69.42
No
113
249.1
117.69
2.5
1
90
CL100250
Full Production
4
10
10
25
17.5
PM8
19
API_blend_40pct
0.38
mixed
0.3
0.52
10
15
1
1.8
0.4069
0.5289
0.5931
4.12
32.42
65
No
148.2
326.7
74.35
2.5
1
91
CL100250
Full Production
4
10
10
25
17.5
PM8
19
API_blend_40pct
0.38
mixed
0.5
0.87
6
75
1
1.47
0.4573
0.5945
0.5427
3.09
30.37
70.71
No
156.2
344.4
85.14
2.5
1
92
CL100250
Full Production
4
10
10
25
17.5
PM8
19
API_blend_40pct
0.38
mixed
0.85
1.47
6
75
0.8
1.78
0.4657
0.6054
0.5343
4.09
29.96
71.2
No
157.3
346.7
109.95
2.5
1
93
CL100250
Full Production
4
10
10
25
17.5
PM8
19
API_blend_40pct
0.38
mixed
0.3
0.52
6
50
1
1.26
0.4412
0.5735
0.5588
3.39
30.94
68.87
No
146
321.8
75.5
2.5
3
94
CL100250
Full Production
4
10
10
25
17.5
PM8
19
API_blend_40pct
0.38
mixed
0.5
0.87
4
50
0.8
1.74
0.4122
0.5359
0.5878
3.77
33.37
65.15
No
126.8
279.5
104.91
2.5
3
95
CL100250
Full Production
4
10
10
25
17.5
PM8
19
API_blend_40pct
0.38
mixed
0.5
0.87
10
100
1
1.25
0.4552
0.5918
0.5448
3.11
30.4
69.06
No
202.1
445.6
65.8
2.5
1
96
CL100250
Full Production
4
10
10
25
17.5
PM8
19
API_blend_40pct
0.38
mixed
1
1.73
10
15
1
1.36
0.5218
0.6784
0.4782
4.27
26.53
73.35
No
143.6
316.5
132.33
2.5
2
97
CL100250
Full Production
4
10
10
25
17.5
PM8
19
API_blend_40pct
0.38
mixed
1
1.73
8
100
1.2
1.26
0.4892
0.636
0.5108
3.68
28.29
70.74
No
182.4
402.1
104.17
2.5
3
98
CL100250
Full Production
4
10
10
25
17.5
PM8
19
API_blend_40pct
0.38
mixed
1
1.73
2
15
1
1.3
0.5268
0.6848
0.4732
3.6
30.53
68.21
No
91.4
201.5
207.92
2.5
1
99
CL100250
Full Production
4
10
10
25
17.5
PM8
19
API_blend_40pct
0.38
mixed
0.5
0.87
4
50
0.8
1.72
0.4183
0.5438
0.5817
3.8
31.77
68.45
No
129.4
285.2
102.81
2.5
1
100
CL100250
Full Production
4
10
10
25
17.5
PM8
19
API_blend_40pct
0.38
mixed
0.3
0.52
6
100
0.6
1.45
0.4008
0.5211
0.5992
5.4
31.92
67.97
No
171.3
377.6
64.34
2.5
3
End of preview. Expand in Data Studio

IPA Pharmaceutical Roller Compactor Platform: Scale-Up & Performance (Synthetic)

Version: 1.0 Publisher: Innovative Process Applications (IPA) License: Creative Commons Attribution 4.0 International (CC BY 4.0)

⚠️ This dataset is 100% synthetic and intended for educational use only. Generated from IPA's published CL-series specifications and standard compaction physics — not real production or clinical batch data.

What's in this dataset

3,000 simulated pharmaceutical roller compaction runs spanning IPA's complete CL-series platform — from R&D lab (CL25150, 5 HP) through full production (CL100250, 25 HP) — across 5 pharma/nutraceutical materials and the full operating envelope of twin-feed-screw process parameters.

Equipment specifications (from IPA published data)

Model Roll Size Max Pressure Integrated Mill Power Scale
CL25150 1"×6" (2.5×15 cm) 17.5 kN/cm None 5 HP R&D / Lab
CL30200 1"×8" (3×20 cm) 17.5 kN/cm PM3 2.75 HP Pilot
CL50200 2"×8" (5×20 cm) 26.0 kN/cm PM6 12 HP Pilot / Small Prod
CL75200 3"×8" (7.5×20 cm) 15.0 kN/cm PM6 20 HP Production
CL100250 4"×10" (10×25 cm) 17.5 kN/cm PM8 25 HP Full Production

Column descriptions

Column Units Description
compactor_model — IPA CL-series model
scale — R&D / Lab, Pilot, Production, Full Production
roll_diameter_in / _cm in / cm Roll diameter
roll_width_in / _cm in / cm Roll width
max_roll_pressure_kn_cm kN/cm Maximum specific compaction force
integrated_mill — PM-series in-air impact mill (or None)
total_power_kw kW Total system power
material — Pharma material identifier
feed_density_gcc g/cc Feed powder bulk density
deformation_type — Plastic, brittle, or mixed
roll_pressure_fraction — Fraction of max pressure applied (0.3–1.0)
scf_kn_cm kN/cm Actual specific compaction force
roll_speed_rpm rpm Roll rotation speed
hfs_speed_rpm rpm Horizontal feed screw speed (controls throughput)
vfs_hfs_ratio — Vertical/horizontal feed screw speed ratio (controls pre-compression)
gap_width_mm mm Roll gap
ribbon_rel_density — Relative density (fraction of true density)
ribbon_density_gcc g/cc Absolute ribbon density
ribbon_porosity — 1 − relative density
density_cv_pct % Across-ribbon density uniformity
fines_pct % Fines fraction after milling
granule_yield_pct % Usable granule yield
in_zinchuk_window Yes/No Ribbon RD in 0.60–0.80 tabletability range
throughput_kg_hr / _lbs_hr kg/hr / lbs/hr Mass throughput
specific_energy_kwh_tonne kWh/tonne Energy efficiency
changeover_time_hr hours Estimated changeover time

IPA platform advantages demonstrated in the data

  1. Twin feed screw (HFS + VFS): Independent control of throughput (HFS) and pre-compression (VFS) produces a uniquely tunable operating space. The VFS/HFS ratio is a key process parameter not available on single-screw compactors.

  2. Scalable platform: Consistent ribbon quality (CV%, yield) across the CL25150 → CL100250 range, enabling direct R&D-to-production scale-up.

  3. Integrated in-air impact milling: PM-series mills minimize heat generation and maximize granule yield with precise PSD control.

  4. Efficient changeover: Modular design enables fast product changeover, critical for multi-product pharma facilities.

  5. Low bulk density capability: Twin screw design is proven efficient with light powders (feed density 0.3–0.5 g/cc) containing high air content.

Cross-links

  • Kaggle: [link after publication]
  • Hugging Face: [link after publication]
  • Zenodo: [link after publication]
  • GitHub: [link after publication]
  • IPA website: https://www.innovativeprocess.com

Citation

Innovative Process Applications (2026). IPA Pharmaceutical Roller Compactor Platform: Scale-Up & Performance (Synthetic), v1.0. CC BY 4.0. https://www.innovativeprocess.com
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