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26950753
Toward an understanding of anticipatory pleasure deficits in schizophrenia: Memory, prospection, and emotion experience.
Anticipatory pleasure deficits have been observed in people with schizophrenia. Less is known about the extent to which interrelated processes that comprise anticipatory pleasure, including memory, prospection, and emotion experience are disrupted. We asked people with (n = 32) and without (n = 29) schizophrenia or sch...
[ 9, 9669, 2, 3, 35, 1666, 8500, 160, 1667, 9671, 3258 ]
[ "Adult", "Anhedonia", "Female", "Humans", "Male", "Memory", "Memory, Episodic", "Middle Aged", "Neuropsychological Tests", "Pleasure", "Schizophrenic Psychology" ]
{ "A": 0, "B": 1, "C": 1, "D": 0, "E": 0, "F": 1, "G": 0, "H": 0, "I": 0, "J": 0, "L": 0, "M": 1, "N": 0, "Z": 0 }
666570
Plasma testosterone level and sexual behavior of couples.
Eleven couples, ages 21-31 years and married for at least 1 year, were studied intensively over a three menstrual cycle period from both an endocrine and a sexual behavioral standpoint. Each subject was interviewed individually and had a blood sample drawn twice weekly. Interviews were rated independently by two psychi...
[ 2681, 9, 2569, 765, 2, 3, 271, 496, 2399, 35, 4706, 674, 1165, 675, 9995, 844, 4595 ]
[ "Adrenal Cortex", "Adult", "Emotions", "Estradiol", "Female", "Humans", "Hydrocortisone", "Interpersonal Relations", "Libido", "Male", "Menstruation", "Ovulation", "Personality", "Progesterone", "Self-Assessment", "Sexual Behavior", "Testosterone" ]
{ "A": 1, "B": 1, "C": 0, "D": 1, "E": 0, "F": 1, "G": 1, "H": 0, "I": 0, "J": 0, "L": 0, "M": 1, "N": 0, "Z": 0 }
3120057
Characterization of capsaicin-sensitive neurones in adult rat dorsal root ganglion cultures.
Two populations of neurones can be distinguished in sections of dorsal root ganglia (DRG) by light microscopy and immunofluorescence techniques: large light (neurofilament-positive) and small dark (neurofilament-negative) neurones. This paper shows that corresponding populations can be seen in cultures of adult rat DRG...
[ 30, 622, 1522, 51, 12162, 1143, 4, 15244, 3078, 1144, 4731, 43, 700 ]
[ "Animals", "Antibodies, Monoclonal", "Capsaicin", "Cells, Cultured", "Cobalt", "Ganglia, Spinal", "Immunohistochemistry", "Intermediate Filament Proteins", "Neurofilament Proteins", "Neurons", "Neurotoxins", "Rats", "Rats, Inbred Strains" ]
{ "A": 1, "B": 1, "C": 0, "D": 1, "E": 1, "F": 0, "G": 0, "H": 1, "I": 0, "J": 0, "L": 0, "M": 0, "N": 0, "Z": 0 }
7476775
[Reconstruction of the oral cavity: the free radial forearm flap versus the free jejunal flap].
The concentration in a restricted area such as the oral cavity of the essential anatomic structures for mastication, deglutition, speech, salivary drainage and respiration makes it indispensable to ensure not only the structural reconstruction of the region but also, and above all, a functional reconstruction of the an...
[ 9, 133, 5281, 2, 163, 887, 3, 2362, 35, 7113, 160, 4873, 2122, 4434 ]
[ "Adult", "Aged", "Chemotherapy, Adjuvant", "Female", "Follow-Up Studies", "Forearm", "Humans", "Jejunum", "Male", "Microsurgery", "Middle Aged", "Mouth", "Mouth Neoplasms", "Surgical Flaps" ]
{ "A": 1, "B": 1, "C": 1, "D": 0, "E": 1, "F": 0, "G": 0, "H": 0, "I": 0, "J": 0, "L": 0, "M": 1, "N": 1, "Z": 0 }
22280555
A genome triplication associated with early diversification of the core eudicots.
BACKGROUND: Although it is agreed that a major polyploidy event, gamma, occurred within the eudicots, the phylogenetic placement of the event remains unclear.RESULTS: To determine when this polyploidization occurred relative to speciation events in angiosperm history, we employed a phylogenomic approach to investigate ...
[ 2476, 2044, 1131, 4915, 6701, 1875, 1035, 2731, 13441 ]
[ "Evolution, Molecular", "Gene Duplication", "Gene Expression Profiling", "Genetic Speciation", "Genome, Plant", "Magnoliopsida", "Phylogeny", "Plant Proteins", "Polyploidy" ]
{ "A": 0, "B": 1, "C": 1, "D": 1, "E": 1, "F": 0, "G": 1, "H": 0, "I": 0, "J": 0, "L": 1, "M": 0, "N": 0, "Z": 0 }
25367544
Parent-implemented social intervention for toddlers with autism: an RCT.
OBJECTIVES: To compare the effects of two 9-month parent-implemented interventions within the Early Social Interaction (ESI) Project. Both individual-ESI, offered 2 or 3 times per week at home or in the community, and group-ESI, offered once per week in a clinic, taught parents how to embed strategies to support social...
[ 5460, 4416, 19831, 3611, 2, 321, 163, 5217, 3, 14, 496, 35, 258, 11392 ]
[ "Child Development Disorders, Pervasive", "Community Mental Health Services", "Education, Nonprofessional", "Evidence-Based Practice", "Female", "Florida", "Follow-Up Studies", "Home Care Services", "Humans", "Infant", "Interpersonal Relations", "Male", "Michigan", "Psychotherapy, Group" ]
{ "A": 0, "B": 1, "C": 0, "D": 0, "E": 1, "F": 1, "G": 0, "H": 1, "I": 1, "J": 0, "L": 0, "M": 1, "N": 1, "Z": 1 }
31770169
How Often Are Study Design and Level of Evidence Misreported in the Pediatric Orthopaedic Literature?
BACKGROUND: Observational studies are the most commonly used study designs in the pediatric orthopaedic literature. The differences between observational study designs are important but not widely understood, leading to potential discrepancies between the reported and actual study design. Study design misclassification...
[ 493, 104, 2867, 3, 3646, 2615, 6605, 6421, 1159 ]
[ "Biomedical Research", "Child", "Evidence-Based Medicine", "Humans", "Journal Impact Factor", "Observational Studies as Topic", "Orthopedics", "Pediatrics", "Research Design" ]
{ "A": 0, "B": 1, "C": 0, "D": 0, "E": 1, "F": 0, "G": 0, "H": 1, "I": 0, "J": 0, "L": 1, "M": 1, "N": 1, "Z": 0 }
16407218
Interaction of mannan binding lectin with alpha2 macroglobulin via exposed oligomannose glycans: a conserved feature of the thiol ester protein family?
The serum collectin mannan-binding lectin (MBL) binds to oligomannose and GlcNAc-terminating glycans present on microorganisms. Using a commercial affinity chromatography resin containing immobilized MBL we screened human and mouse serum for endogenous MBL-binding targets. We isolated the serum protease inhibitor alpha...
[ 30, 6241, 626, 3480, 2724, 777, 8357, 6829, 6243, 3, 1707, 2853, 6245, 17921, 1930, 36, 4879, 4922, 372, 373, 954, 653, 4345, 4757, 12800 ]
[ "Animals", "Asparagine", "Chromatography, High Pressure Liquid", "Complement System Proteins", "Conserved Sequence", "Electrophoresis, Polyacrylamide Gel", "Esters", "Glycoside Hydrolases", "Glycosylation", "Humans", "Hydrogen-Ion Concentration", "Lectins", "Mannose", "Mannose-Binding Lect...
{ "A": 0, "B": 1, "C": 0, "D": 1, "E": 1, "F": 0, "G": 1, "H": 1, "I": 0, "J": 0, "L": 0, "M": 0, "N": 1, "Z": 0 }
12099910
Direction-specific motion blindness induced by focal stimulation of human extrastriate cortex.
Motion blindness (MB) or akinetopsia is the selective disturbance of visual motion perception while other features of the visual scene such as colour and shape are normally perceived. Chronic and transient forms of MB are characterized by a global deficit of direction discrimination (pandirectional), which is generally...
[ 9, 19589, 1601, 147, 2267, 2, 558, 3, 3053, 4693, 6942, 5406, 3623, 6134, 3349, 3414 ]
[ "Adult", "Blindness, Cortical", "Brain Mapping", "Electric Stimulation", "Epilepsy", "Female", "Functional Laterality", "Humans", "Motion Perception", "Orientation", "Perceptual Disorders", "Psychomotor Performance", "Temporal Lobe", "Visual Cortex", "Visual Fields", "Visual Pathways" ...
{ "A": 1, "B": 1, "C": 1, "D": 0, "E": 1, "F": 1, "G": 1, "H": 0, "I": 0, "J": 0, "L": 0, "M": 1, "N": 0, "Z": 0 }
927976
Detergent enema: a cause of caustic colitis.
A 5-year-old boy developed acute colitis followed by stricture formation as a result of a detergent enema. The acute phase of the caustic induced colitis was reproduced in the dog and the rat using full strength and diluted detergent enemas. The severity of the experimental colitis was shown to be directly related to t...
[ 30, 105, 7768, 2875, 3810, 146, 8358, 3, 35, 43 ]
[ "Animals", "Child, Preschool", "Colitis", "Colon", "Detergents", "Dogs", "Enema", "Humans", "Male", "Rats" ]
{ "A": 1, "B": 1, "C": 1, "D": 1, "E": 1, "F": 0, "G": 0, "H": 0, "I": 0, "J": 1, "L": 0, "M": 1, "N": 0, "Z": 0 }
16495164
Hypovitaminosis D osteopathy: is it mediated through PTH, lean mass, or is it a direct effect?
Hypovitaminosis D is increasing worldwide and is associated with low bone mass. The effects of hypovitaminosis D on bone might be direct or mediated through decreased muscle mass and function and/or secondary hyperparathyroidism. This study systematically investigated the relative contribution of lean mass, PTH, and th...
[ 223, 133, 310, 10, 225, 863, 551, 2, 868, 3, 12830, 322, 35, 19, 598, 14845, 417, 10061, 647, 24, 25 ]
[ "Absorptiometry, Photon", "Aged", "Aged, 80 and over", "Alkaline Phosphatase", "Body Composition", "Bone Density", "Calcium", "Female", "Femur", "Humans", "Lebanon", "Linear Models", "Male", "Parathyroid Hormone", "Retrospective Studies", "Rickets", "Sex Factors", "Thinness", "Ur...
{ "A": 1, "B": 1, "C": 1, "D": 1, "E": 1, "F": 0, "G": 1, "H": 0, "I": 0, "J": 0, "L": 0, "M": 1, "N": 1, "Z": 1 }
17659624
Combining spin echoes with gradient echoes in the context of the global coherent free precession pulse sequence.
To extend the signal longevity of magnetically excited spins in flowing fluids while in a state of global coherent free precession (GCFP), a refocusing radiofrequency (RF) pulse and bipolar gradient waveforms were combined with the GCFP sequence. The data demonstrate that RF refocusing in the presence of flowing blood ...
[ 30, 146, 3769, 1543 ]
[ "Animals", "Dogs", "Magnetic Resonance Angiography", "Phantoms, Imaging" ]
{ "A": 0, "B": 1, "C": 0, "D": 0, "E": 1, "F": 0, "G": 0, "H": 0, "I": 0, "J": 0, "L": 0, "M": 0, "N": 0, "Z": 0 }
985808
Induction of interferon in ovine and human lymphocyte cultures by mycoplasmas.
Mycoplasma pneumoniae, Acholeplasma laidlawii, M. arthritidis, and M. pulmonis were shown to induce interferon in the lymphocyte fraction of ovine peripheral blood leukocytes, but not in the polymorphonuclear leukocyte fraction. Human peripheral blood lymphocytes produced significant levels of interferon in response to...
[ 12558, 30, 51, 3, 2289, 335, 3208, 2085, 1566, 1722 ]
[ "Acholeplasma laidlawii", "Animals", "Cells, Cultured", "Humans", "Interferons", "Lymphocytes", "Mycoplasma", "Neutrophils", "Sheep", "Species Specificity" ]
{ "A": 1, "B": 1, "C": 0, "D": 1, "E": 0, "F": 0, "G": 1, "H": 0, "I": 0, "J": 0, "L": 0, "M": 0, "N": 0, "Z": 0 }
9620308
Regulatory effects of heat on normal human melanocyte growth and melanogenesis: comparative study with UVB.
Although energy-rich ultraviolet B (UVB) is considered to be primarily responsible for most of the effects associated with solar radiation, small energy recorded as heat appears to contribute to the biologic effects of solar radiation on the skin. We compared the effects of heat and UVB on normal human melanocyte funct...
[ 1503, 51, 1496, 9750, 854, 3, 4560, 4050, 8701, 1028, 7942, 15505, 6040, 451, 312, 4055, 6, 2383 ]
[ "Cell Division", "Cells, Cultured", "Coculture Techniques", "Dihydroxyphenylalanine", "Hot Temperature", "Humans", "Keratinocytes", "Melanins", "Melanocytes", "Membrane Glycoproteins", "Monophenol Monooxygenase", "Oncogene Protein p21(ras)", "Oxidoreductases", "Proteins", "Skin", "Skin...
{ "A": 1, "B": 1, "C": 0, "D": 1, "E": 1, "F": 0, "G": 1, "H": 0, "I": 0, "J": 0, "L": 0, "M": 0, "N": 1, "Z": 0 }
25771794
abiliti Closed-Loop Gastric Electrical Stimulation System for Treatment of Obesity: Clinical Results with a 27-Month Follow-Up.
BACKGROUND: The aim of the study was to evaluate the safety and effectiveness of a novel closed-loop gastric electric stimulation device (abiliti system) featuring a transgastric sensor to detect food intake and an accelerometer to record physical activity to induce and maintain lifestyle changes to treat obesity.METHO...
[ 9, 5535, 3097, 1177, 1379, 2, 163, 3, 7330, 2014, 35, 160, 3424, 66, 483, 599, 484, 144, 601 ]
[ "Adult", "Electric Stimulation Therapy", "Electrodes, Implanted", "Exercise", "Feeding Behavior", "Female", "Follow-Up Studies", "Humans", "Hunger", "Life Style", "Male", "Middle Aged", "Obesity, Morbid", "Prostheses and Implants", "Quality of Life", "Stomach", "Surveys and Questionn...
{ "A": 1, "B": 1, "C": 1, "D": 0, "E": 1, "F": 1, "G": 1, "H": 0, "I": 1, "J": 0, "L": 0, "M": 1, "N": 1, "Z": 0 }
2975010
Consequences of chronic phenobarbital blockade of spontaneous motility in chick embryos for the development of central motor output activity.
The consequences of the chronic continuous administration of Na+-phenobarbital in an average dose of 9.8 mg/kg e.w./24 h were studied in chick embryos. Administration was always started on the 4th day of incubation and lasted 4-12 days. Spontaneous motility was tested in 13- and 17-day-old embryos. The continuous, chro...
[ 30, 237, 781, 1063, 2370, 17593, 10285, 2601, 17594, 5035 ]
[ "Animals", "Bicuculline", "Central Nervous System", "Chick Embryo", "Motor Activity", "Oxazepam", "Pentylenetetrazole", "Phenobarbital", "Strychnine", "gamma-Aminobutyric Acid" ]
{ "A": 1, "B": 1, "C": 0, "D": 1, "E": 0, "F": 1, "G": 1, "H": 0, "I": 0, "J": 0, "L": 0, "M": 0, "N": 0, "Z": 0 }
2749074
The control of confounding by intermediate variables.
In epidemiologic studies of the effect of an exposure on disease, the crude association of exposure with disease may fail to reflect a causal association due to confounding by one or more covariates. Most previous discussions of confounding in the epidemiologic literature have considered only point exposure studies, th...
[ 2711, 5677, 8243, 3, 379, 3347, 2614, 1188, 177 ]
[ "Data Interpretation, Statistical", "Epidemiologic Methods", "Epidemiology", "Humans", "Longitudinal Studies", "Mathematics", "Models, Statistical", "Random Allocation", "Risk Factors" ]
{ "A": 0, "B": 1, "C": 0, "D": 0, "E": 1, "F": 0, "G": 0, "H": 1, "I": 0, "J": 0, "L": 1, "M": 0, "N": 1, "Z": 0 }
3972334
Prolactin levels in pregnancy: comparison of normal subjects with patients having micro- or macroadenomas after early bromocriptine withdrawal.
14 previously infertile patients, 11 with radiologically abnormal fossae, and a mean prolactin level of 761 ng/ml (range 49-4,500 ng/ml) conceived on 19 occasions during bromocriptine treatment. So far, 15 healthy infants have been delivered. Treatment was withdrawn soon after conception and the subsequent prolactin ch...
[ 1093, 9, 14400, 2, 3, 2449, 1426, 20, 12065, 1427 ]
[ "Adenoma", "Adult", "Bromocriptine", "Female", "Humans", "Infertility, Female", "Pituitary Neoplasms", "Pregnancy", "Pregnancy Complications, Neoplastic", "Prolactin" ]
{ "A": 0, "B": 1, "C": 1, "D": 1, "E": 0, "F": 0, "G": 1, "H": 0, "I": 0, "J": 0, "L": 0, "M": 1, "N": 0, "Z": 0 }
11564589
Cerebrospinal fluid S-100beta and its relationship with AIDS dementia complex.
BACKGROUND: The astrocyte is thought to be important in AIDS dementia complex (ADC) pathogenesis on the basis of ADC neuropathology and cell culture models putatively because HIV can infect astrocytes leading to a compromise of their physiological detoxifying and neuronal support functions. Confirmatory in vivo data ar...
[ 9830, 861, 2439, 3314, 3, 1528, 14678, 8325, 1907 ]
[ "AIDS Dementia Complex", "Biomarkers", "Disease Progression", "HIV-1", "Humans", "Nerve Growth Factors", "S100 Calcium Binding Protein beta Subunit", "S100 Proteins", "Viral Load" ]
{ "A": 0, "B": 1, "C": 1, "D": 1, "E": 1, "F": 1, "G": 1, "H": 0, "I": 0, "J": 0, "L": 0, "M": 0, "N": 0, "Z": 0 }
26941216
Considerations for conducting qualitative research with pediatric patients for the purpose of PRO development.
PURPOSE: To provide an overview of methodological considerations when conducting qualitative research with pediatric patients for the purpose of patient-reported outcome measure developmentMETHODS: A literature review of qualitative methods in pediatric measure development was completed. Eight clinicians providing care...
[ 104, 105, 1254, 2, 3, 4340, 35, 4179, 6421, 1579, 483, 1159 ]
[ "Child", "Child, Preschool", "Communication", "Female", "Humans", "Interviews as Topic", "Male", "Patient Reported Outcome Measures", "Pediatrics", "Qualitative Research", "Quality of Life", "Research Design" ]
{ "A": 0, "B": 1, "C": 0, "D": 0, "E": 1, "F": 1, "G": 0, "H": 1, "I": 1, "J": 0, "L": 1, "M": 1, "N": 1, "Z": 0 }
17029463
Dissociation of heme from gaseous myoglobin ions studied by infrared multiphoton dissociation spectroscopy and Fourier-transform ion cyclotron resonance mass spectrometry.
Detachment of heme prosthetic groups from gaseous myoglobin ions has been studied by collision-induced dissociation and infrared multiphoton dissociation in combination with Fourier-transform ion cyclotron resonance mass spectrometry. Multiply charged holomyoglobin ions (hMbn+) were generated by electrospray ionization...
[ 4993, 248, 3502, 1930, 5687, 5685, 5688, 1124 ]
[ "Apoproteins", "Gases", "Heme", "Mass Spectrometry", "Myoglobin", "Nitrogen", "Photons", "Spectrum Analysis" ]
{ "A": 0, "B": 0, "C": 0, "D": 1, "E": 1, "F": 0, "G": 1, "H": 0, "I": 0, "J": 0, "L": 0, "M": 0, "N": 0, "Z": 0 }
16556232
Oxidative stress promotes degradation of the Irr protein to regulate haem biosynthesis in Bradyrhizobium japonicum.
The haem proteins catalase and peroxidase are stress response proteins that detoxify reactive oxygen species. In the bacterium Bradyrhizobium japonicum, expression of the gene encoding the haem biosynthesis enzyme delta-aminolevulinic acid dehydratase (ALAD) is normally repressed by the Irr protein in iron-limited cell...
[ 819, 11783, 3067, 1279, 3502, 855, 2654, 953, 857, 10166, 364, 1521 ]
[ "Bacterial Proteins", "Bradyrhizobium", "Culture Media", "Gene Expression Regulation, Bacterial", "Heme", "Hydrogen Peroxide", "Iron", "Oxidation-Reduction", "Oxidative Stress", "Porphobilinogen Synthase", "Reactive Oxygen Species", "Receptor, Insulin" ]
{ "A": 0, "B": 1, "C": 0, "D": 1, "E": 1, "F": 0, "G": 1, "H": 0, "I": 0, "J": 0, "L": 0, "M": 0, "N": 0, "Z": 0 }
985400
Freezing temperature of finger skin.
In 45 subjects, 154 frostnips of the finger were induced by cooling in air at -15 degrees C with various wind speeds. The mean supercooled skin temperature at which frostnip appeared was -9.4 degrees C. The mean skin temperature rise due to heat of fusion at ice crystallization was 5.3 degrees C. The skin temperature r...
[ 9, 886, 888, 3, 35, 160, 836, 4283, 3867 ]
[ "Adult", "Cold Temperature", "Frostbite", "Humans", "Male", "Middle Aged", "Skin Temperature", "Vasomotor System", "Wind" ]
{ "A": 1, "B": 1, "C": 1, "D": 0, "E": 0, "F": 0, "G": 1, "H": 0, "I": 0, "J": 0, "L": 0, "M": 1, "N": 1, "Z": 0 }
9166839
Clonal proliferation and cytokine requirement of murine progenitors for natural killer cells.
We have established a clonal cell culture system that supports the proliferation of committed natural killer (NK) cell progenitors of mice to investigate the pathway and cytokine regulation of NK cell development. Day 14 fetal thymocytes cultured in methylcellulose with interleukin-7 (IL-7), IL-15, and steel factor (SF...
[ 30, 4075, 1503, 826, 866, 134, 443, 1596, 36 ]
[ "Animals", "Cell Culture Techniques", "Cell Division", "Clone Cells", "Cytokines", "Dose-Response Relationship, Drug", "Hematopoietic Stem Cells", "Killer Cells, Natural", "Mice" ]
{ "A": 1, "B": 1, "C": 0, "D": 1, "E": 1, "F": 0, "G": 1, "H": 0, "I": 0, "J": 0, "L": 0, "M": 0, "N": 0, "Z": 0 }
2908581
Leukocyte subsets in the granulomatous response produced after inoculation with Mycobacterium leprae-BCG in lepromatous patients.
Leukocyte subsets present in the granulomatous response produced after the inoculation of a mixture of Mycobacterium leprae and BCG in lepromatous leprosy patients were characterized in situ using monoclonal antibodies and an immunoperoxidase technique. The granuloma produced after M. leprae-BCG inoculation showed a di...
[ 622, 1655, 8324, 3, 2947, 922, 5651, 5360, 751, 3712, 5361, 3629, 4955, 1555 ]
[ "Antibodies, Monoclonal", "CD4-Positive T-Lymphocytes", "Granuloma", "Humans", "Immunity, Cellular", "Immunoenzyme Techniques", "Langerhans Cells", "Leprosy, Lepromatous", "Leukocytes", "Mycobacterium bovis", "Mycobacterium leprae", "T-Lymphocytes, Cytotoxic", "T-Lymphocytes, Helper-Inducer"...
{ "A": 1, "B": 1, "C": 1, "D": 1, "E": 1, "F": 0, "G": 1, "H": 0, "I": 0, "J": 0, "L": 0, "M": 0, "N": 0, "Z": 0 }
8141178
Urinary N-acetyl-glucosaminidase excretion and environmental lead exposure. Green Cross Health Service Association Study Group.
To understand the relationship between chronic low-level lead exposure and renal function, residents living nearby a lead battery factory for more than 10 years were selected and entered in this cross-section study. The residents living in the 1st village, within 500 m from the factory, were grouped in group 1; those i...
[ 6240, 4598, 12, 2430, 7746, 2, 3, 3030, 2387, 4885, 35, 160, 3244 ]
[ "Acetylglucosaminidase", "Body Burden", "Cross-Sectional Studies", "Environmental Exposure", "Environmental Pollution", "Female", "Humans", "Kidney Failure, Chronic", "Lead", "Lead Poisoning", "Male", "Middle Aged", "Taiwan" ]
{ "A": 0, "B": 1, "C": 1, "D": 1, "E": 1, "F": 0, "G": 0, "H": 0, "I": 0, "J": 0, "L": 0, "M": 1, "N": 1, "Z": 1 }
18989826
Isolation and structure determination of the biologically active sphingolipids from marine sponge Haliclona species.
In a continuation to our study on the marine sponge Haliclona species we have isolated three new cytotoxic components of sphingolipids (1-3). Methanolysis of the sphingolipid 1a-d in methanol produces fatty acid methyl ester. GC/MS was used to determine the length. The structure of each isolated compound has been deter...
[ 30, 4172, 13176, 8361, 36, 607, 4996, 7279, 10442 ]
[ "Animals", "Gas Chromatography-Mass Spectrometry", "Haliclona", "Marine Biology", "Mice", "Molecular Structure", "Nuclear Magnetic Resonance, Biomolecular", "Oceans and Seas", "Sphingolipids" ]
{ "A": 0, "B": 1, "C": 0, "D": 1, "E": 1, "F": 0, "G": 1, "H": 1, "I": 0, "J": 0, "L": 0, "M": 0, "N": 0, "Z": 1 }
506494
[Increased transaminase activity in the patients and personnel of dialysis centers and problem of its assessment].
Within the general hepatitis prevention on dialysis wards regular controls of the liver values and the HBsAG/AK are necessary for the patients and the personnel. The general symptom which is frequently found in these cases -- increased transaminase -- demands a diagnostic clarification and the exclusion of an acute vir...
[ 4436, 10, 4438, 5730, 207, 582, 10403, 1227, 3, 275, 18222, 14147 ]
[ "Alanine Transaminase", "Alkaline Phosphatase", "Bilirubin", "Clinical Enzyme Tests", "Diagnosis, Differential", "Enzyme Activation", "Hepatitis A", "Hepatitis B Surface Antigens", "Humans", "Renal Dialysis", "Thymol", "Transaminases" ]
{ "A": 0, "B": 0, "C": 0, "D": 0, "E": 0, "F": 0, "G": 0, "H": 0, "I": 0, "J": 0, "L": 0, "M": 0, "N": 0, "Z": 0 }
9145909
Subtype-specific intracellular trafficking of alpha2-adrenergic receptors.
The three alpha2-adrenergic receptor subtypes (alpha2a, alpha2b, and alpha2c) are highly homologous G protein-coupled receptors. These receptors all couple to pertussis toxin-sensitive G proteins and have relatively similar pharmacological properties. To further explore functional differences between these receptors, w...
[ 28, 30, 1261, 4531, 657, 1723, 146, 4348, 3804, 1499, 3, 4, 36, 37, 43, 15027 ]
[ "Amino Acid Sequence", "Animals", "Biological Transport", "COS Cells", "Cell Line", "Culture Techniques", "Dogs", "Endocytosis", "Endoplasmic Reticulum", "Fibroblasts", "Humans", "Immunohistochemistry", "Mice", "Molecular Sequence Data", "Rats", "Receptors, Adrenergic, alpha-2" ]
{ "A": 1, "B": 1, "C": 0, "D": 1, "E": 1, "F": 0, "G": 1, "H": 1, "I": 0, "J": 0, "L": 1, "M": 0, "N": 0, "Z": 0 }
24512497
Nonalcoholic Fatty liver disease is associated with increased carotid intima-media thickness only in type 2 diabetic subjects with insulin resistance.
CONTEXT: The association between nonalcoholic fatty liver disease (NAFLD) and subclinical atherosclerosis in type 2 diabetes is controversial.OBJECTIVE: The objective of the study was to investigate the participation of insulin resistance in the association of NAFLD and the carotid atherosclerotic burden in a large coh...
[ 9, 133, 975, 976, 2692, 1778, 3043, 2, 3, 1520, 35, 3992, 160, 4246, 177 ]
[ "Adult", "Aged", "Carotid Arteries", "Carotid Artery Diseases", "Carotid Intima-Media Thickness", "Diabetes Mellitus, Type 2", "Fatty Liver", "Female", "Humans", "Insulin Resistance", "Male", "Metabolic Syndrome", "Middle Aged", "Non-alcoholic Fatty Liver Disease", "Risk Factors" ]
{ "A": 1, "B": 1, "C": 1, "D": 0, "E": 1, "F": 0, "G": 1, "H": 0, "I": 0, "J": 0, "L": 0, "M": 1, "N": 1, "Z": 0 }
28268338
Origami microfluidic paper-analytical-devices (omPAD) for sensing and diagnostics.
Recent research activities in the area of low-cost sensing and diagnostics that are realized on cellulosic paper substrate are presented. First a three-dimensional origami paper-based analytical device (omPAD) with multiple electrochemical sensors, an integrated sample reservoir and tight integration with a custom CMOS...
[ 246, 1924, 2952, 2088, 2953, 919, 2954, 2955, 2956, 2957, 803, 1998, 2958 ]
[ "Biosensing Techniques", "Dopamine", "Electrochemical Techniques", "Electrodes", "Imaging, Three-Dimensional", "Metals", "Microfluidic Analytical Techniques", "Microtechnology", "Optical Phenomena", "Oxides", "Paper", "Point-of-Care Systems", "Semiconductors" ]
{ "A": 0, "B": 0, "C": 0, "D": 1, "E": 1, "F": 0, "G": 1, "H": 1, "I": 0, "J": 1, "L": 1, "M": 0, "N": 1, "Z": 0 }
30115351
Effectiveness of Psychological Adaptation Model of Mental Health Nursing for nurse survivors experiencing post-earthquake disaster post-traumatic stress syndrome.
OBJECTIVE: The study to assess the effectiveness of psychological adaptation model of mental health nursing for nurse survivors experiencing post-earthquake post-traumatic stress syndrome (PTSS).METHOD: This study used a quasi-experimental pre- post-test without control group method. Respondents amounted to 42 people w...
[ 475, 9, 11391, 2, 3, 8141, 35, 160, 1933, 6516, 8759, 1168, 5233, 27 ]
[ "Adaptation, Psychological", "Adult", "Earthquakes", "Female", "Humans", "Indonesia", "Male", "Middle Aged", "Models, Psychological", "Nurses", "Psychiatric Nursing", "Self Report", "Stress Disorders, Post-Traumatic", "Young Adult" ]
{ "A": 0, "B": 1, "C": 0, "D": 0, "E": 1, "F": 1, "G": 1, "H": 1, "I": 0, "J": 0, "L": 0, "M": 1, "N": 1, "Z": 1 }
31166200
Evaluation of a Novel Medicolegal Death Investigator-Based Suicide Surveillance System to the National Violent Death Reporting System.
The abundance of actionable information available in a medicolegal suicide investigation is often inaccessible and underutilized in public health to the detriment of prevention efforts. Epidemiologists obtained the Washington County subset of the Oregon Violent Death Reporting System (OR-VDRS). To determine if addition...
[ 1204, 2767, 3, 2134, 1272, 177, 4654, 132, 5207, 942 ]
[ "Data Collection", "Databases, Factual", "Humans", "Information Storage and Retrieval", "Population Surveillance", "Risk Factors", "Suicide", "United States", "Violence", "Wounds and Injuries" ]
{ "A": 0, "B": 1, "C": 1, "D": 0, "E": 1, "F": 1, "G": 0, "H": 0, "I": 1, "J": 0, "L": 1, "M": 0, "N": 1, "Z": 1 }
21675592
Radiolocalization of sentinel lymph nodes in clinically N0 laryngeal and hypopharyngeal cancers.
OBJECTIVES: We sought to analyze the characteristics of radioactive lymph nodes with metastatic disease and to explore methods for the localization of sentinel lymph nodes (SLNs) with radionuclide in clinically N0 laryngeal and hypopharyngeal cancer.METHODS: Forty-five patients with T1-T4 and clinically N0 laryngeal an...
[ 9, 133, 207, 2, 163, 3, 10491, 7497, 4661, 1850, 35, 160, 1599, 1187, 397, 1236, 2582, 97, 598, 7927 ]
[ "Adult", "Aged", "Diagnosis, Differential", "Female", "Follow-Up Studies", "Humans", "Hypopharyngeal Neoplasms", "Laryngeal Neoplasms", "Lymph Nodes", "Lymphatic Metastasis", "Male", "Middle Aged", "Neck", "Neoplasm Staging", "Prognosis", "Radionuclide Imaging", "Radiopharmaceuticals...
{ "A": 1, "B": 1, "C": 1, "D": 1, "E": 1, "F": 0, "G": 0, "H": 0, "I": 0, "J": 0, "L": 0, "M": 1, "N": 1, "Z": 0 }
28328837
Atypical presentation of paroxysmal nocturnal hemoglobinuria treated by eculizumab: A case report.
RATIONALE: Paroxysmal nocturnal hemoglobinuria (PNH) is a nonmalignant acquired hematopoietic stem cell disease, which can be revealed by hemolytic anemia, thromboembolism, or bonemarrow failure. Thrombosis can occur at any site, but coronary thrombosis is extremely rare. Controlled trials have demonstrated that eculiz...
[ 133, 3321, 12847, 1233, 10658, 2002, 14943, 3, 1461, 35 ]
[ "Aged", "Antibodies, Monoclonal, Humanized", "Coronary Thrombosis", "Coronary Vessels", "Delayed Diagnosis", "Fatal Outcome", "Hemoglobinuria, Paroxysmal", "Humans", "Immunologic Factors", "Male" ]
{ "A": 1, "B": 1, "C": 1, "D": 1, "E": 1, "F": 0, "G": 0, "H": 0, "I": 0, "J": 0, "L": 0, "M": 1, "N": 1, "Z": 0 }
15774857
Contractile properties of the cultured vascular smooth muscle cells: the crucial role played by RhoA in the regulation of contractility.
Vascular smooth muscle cells (VSMCs) have a remarkable degree of plasticity and in response to vascular injury, they can change to a dedifferentiated state that can be typically seen in cell cultures. Recently, Y27632, a Rho kinase inhibitor, has been reported to preferentially correct hypertension in a hypertensive ra...
[ 3674, 30, 551, 51, 8190, 2665, 6926, 10124, 586, 2629, 139, 1287, 572, 4222, 6311 ]
[ "Amides", "Animals", "Calcium", "Cells, Cultured", "Guanosine 5'-O-(3-Thiotriphosphate)", "Muscle, Smooth, Vascular", "Myocytes, Smooth Muscle", "Myosin Light Chains", "Phosphorylation", "Protein Kinase C", "Pyridines", "RNA Interference", "Swine", "Vasoconstriction", "rhoA GTP-Binding P...
{ "A": 1, "B": 1, "C": 0, "D": 1, "E": 0, "F": 0, "G": 1, "H": 0, "I": 0, "J": 0, "L": 0, "M": 0, "N": 0, "Z": 0 }
3508745
Chronobiological aspects of weight loss in obesity: effects of different meal timing regimens.
A series of short- and long-lasting experimental protocols of different meal timing regimes were performed in obese subjects to assess the possible occurrence of (1) a different metabolic fate of nutrients; (2) a phase shift of circadian rhythms of metabolic and hormonal parameters strictly related to nutrition; (3) a ...
[ 9, 522, 2183, 1308, 5124, 592, 732, 3, 1542, 596, 385, 131, 601 ]
[ "Adult", "Blood Pressure", "Body Temperature", "Circadian Rhythm", "Diet, Reducing", "Eating", "Heart Rate", "Humans", "Models, Biological", "Obesity", "Respiration", "Time Factors", "Weight Loss" ]
{ "A": 0, "B": 1, "C": 1, "D": 0, "E": 1, "F": 0, "G": 1, "H": 0, "I": 0, "J": 0, "L": 0, "M": 1, "N": 0, "Z": 0 }
26931744
Outcome of liver transplantation in patients with hereditary bleeding disorders: a single centre UK experience.
INTRODUCTION: Patients with hereditary bleeding disorders who have developed end-stage liver disease as a consequence of hepatitis C infection (HCV) acquired from factor concentrates prior to the introduction of viral inactivation continue to be referred for liver transplantation.METHODS: A retrospective review of case...
[ 9, 133, 2374, 6716, 4392, 10887, 422, 3, 2375, 2276, 160, 695, 598, 542, 1406 ]
[ "Adult", "Aged", "Carcinoma, Hepatocellular", "End Stage Liver Disease", "Hemophilia A", "Hemophilia B", "Hepatitis C", "Humans", "Liver Neoplasms", "Liver Transplantation", "Middle Aged", "Postoperative Complications", "Retrospective Studies", "Survival Analysis", "United Kingdom" ]
{ "A": 0, "B": 1, "C": 1, "D": 0, "E": 1, "F": 0, "G": 0, "H": 0, "I": 0, "J": 0, "L": 0, "M": 1, "N": 1, "Z": 1 }
11376357
Hair transplantation.
Hair transplantation is a technique in which hair follicles are harvested from the occipital area and re-transplanted in the frontal bald area. Hair transplantation is the most common cosmetic procedure in the United States nowadays despite the fact that it is expensive. Usually, patients need more than one session to ...
[ 9, 16283, 6122, 4811, 12701, 6794, 3, 35, 3579, 6058, 6124, 132 ]
[ "Adult", "Alopecia", "Costs and Cost Analysis", "Cross-Cultural Comparison", "Hair", "Hair Follicle", "Humans", "Male", "Saudi Arabia", "Surgery, Plastic", "Surgical Instruments", "United States" ]
{ "A": 1, "B": 1, "C": 1, "D": 0, "E": 1, "F": 0, "G": 0, "H": 1, "I": 1, "J": 0, "L": 0, "M": 1, "N": 1, "Z": 1 }
24613360
The effect of cultural interaction on cumulative cultural evolution.
Cultural transmission and cultural evolution are important for animals, especially for humans. I developed a new analytical model of cultural evolution, in which each newborn learns cultural traits from multiple individuals (exemplars) in parental generation, individually explores around learned cultural traits, judges...
[ 2132, 8621, 3, 834 ]
[ "Biological Evolution", "Culture", "Humans", "Models, Theoretical" ]
{ "A": 0, "B": 1, "C": 0, "D": 0, "E": 1, "F": 0, "G": 1, "H": 0, "I": 1, "J": 0, "L": 0, "M": 0, "N": 0, "Z": 0 }
8675705
Differential expression of perforin in muscle-infiltrating T cells in polymyositis and dermatomyositis.
Polymyositis (PM) and dermatomyositis (DM) are the prototypical inflammatory diseases of skeletal muscle. In PM, CD8+ T cells invade and destroy muscle fibers, whereas humoral effector mechanisms prevail in DM. We studied the expression of the cytotoxic mediator perforin in inflammatory cells in PM and DM muscle by sem...
[ 439, 8191, 3, 1028, 37, 120, 15105, 449, 16333, 10075, 1047 ]
[ "Base Sequence", "Dermatomyositis", "Humans", "Membrane Glycoproteins", "Molecular Sequence Data", "Muscles", "Perforin", "Polymerase Chain Reaction", "Polymyositis", "Pore Forming Cytotoxic Proteins", "T-Lymphocytes" ]
{ "A": 1, "B": 1, "C": 1, "D": 1, "E": 1, "F": 0, "G": 1, "H": 0, "I": 0, "J": 0, "L": 1, "M": 0, "N": 0, "Z": 0 }
21442223
The relative timing of trunk muscle activation is retained in response to unanticipated postural-perturbations during acute low back pain.
The purpose of this study was to assess the activation of the erector spinae (ES) and external oblique (EO) in response to unanticipated, bi-directional postural perturbations before and after the induction of acute low back pain (LBP) in healthy individuals. An experimental session consisted of a baseline, control, an...
[ 454, 383, 2, 3, 3786, 35, 38, 60, 3188, 3073, 3535, 131, 27 ]
[ "Acute Disease", "Adaptation, Physiological", "Female", "Humans", "Low Back Pain", "Male", "Muscle Contraction", "Muscle, Skeletal", "Postural Balance", "Reaction Time", "Reflex", "Time Factors", "Young Adult" ]
{ "A": 1, "B": 1, "C": 1, "D": 0, "E": 1, "F": 1, "G": 1, "H": 0, "I": 0, "J": 0, "L": 0, "M": 1, "N": 0, "Z": 0 }
23109305
Pelvic fractures at a new level 1 trauma centre: who dies from pelvic trauma? The Inkosi Albert Luthuli Central Hospital experience.
OBJECTIVE: To identify the incidence of pelvic trauma, causes of death and factors predicting death with pelvic fractures.METHODS: All pelvic fractures were retrospectively identified from a registry spanning from March 2007 to August 2009. Data was captured on a proforma. Data for survivors, non-survivors and a subgro...
[ 5584, 3903, 204, 9, 133, 1731, 3658, 104, 105, 2, 6754, 3, 35, 160, 6755, 598, 6955, 5205, 144, 27 ]
[ "Accidental Falls", "Accidents, Traffic", "Adolescent", "Adult", "Aged", "Blood Transfusion", "Cause of Death", "Child", "Child, Preschool", "Female", "Fractures, Bone", "Humans", "Male", "Middle Aged", "Pelvic Bones", "Retrospective Studies", "South Africa", "Trauma Centers", "T...
{ "A": 1, "B": 1, "C": 1, "D": 0, "E": 1, "F": 0, "G": 0, "H": 0, "I": 0, "J": 0, "L": 0, "M": 1, "N": 1, "Z": 1 }
10829850
Transplacental immunity and waning of maternal antibody in measles.
Since transplacental immunity and waning of maternally derived measles specific antibodies play an important role in determining the optimum age for vaccination of infants against measles, a study was carried out in which 150 paired samples and 581 infant serum samples were tested for measles specific antibodies. Out o...
[ 906, 2, 3, 3001, 9674, 14, 229, 379, 8536, 2777, 20, 642, 6678 ]
[ "Age Distribution", "Female", "Humans", "Immunity, Maternally-Acquired", "Immunization Schedule", "Infant", "Infant, Newborn", "Longitudinal Studies", "Measles", "Measles Vaccine", "Pregnancy", "Regression Analysis", "Serologic Tests" ]
{ "A": 0, "B": 1, "C": 1, "D": 1, "E": 1, "F": 0, "G": 1, "H": 0, "I": 1, "J": 0, "L": 0, "M": 1, "N": 1, "Z": 0 }
7720178
A phase I trial of high-dose oral tamoxifen and CHOPE.
Drug resistance is a common phenomenon in clinical oncology. In vitro, tamoxifen has been shown to be an effective inhibitor of P-glycoprotein and a modulator of the multidrug resistance phenotype. We have previously shown that vinblastine can be given safely in combination with tamoxifen at doses that may modulate P-g...
[ 461, 9, 133, 1450, 2398, 76, 1451, 4025, 2, 3, 35, 160, 429, 7407, 2717, 401, 2719 ]
[ "Administration, Oral", "Adult", "Aged", "Antineoplastic Combined Chemotherapy Protocols", "Cyclophosphamide", "Doxorubicin", "Drug Administration Schedule", "Etoposide", "Female", "Humans", "Male", "Middle Aged", "Neoplasms", "Neutropenia", "Prednisone", "Tamoxifen", "Vincristine" ]
{ "A": 0, "B": 1, "C": 1, "D": 1, "E": 1, "F": 0, "G": 0, "H": 0, "I": 0, "J": 0, "L": 0, "M": 1, "N": 0, "Z": 0 }
29571266
Retrieval activates related words more than presentation.
Retrieving information enhances learning more than restudying. One explanation of this effect is based on the role of mediators (e.g., sand-castle can be mediated by beach). Retrieval is hypothesised to activate mediators more than restudying, but existing tests of this hypothesis have had mixed results [Carpenter, S. ...
[ 204, 9, 11030, 3072, 2, 3, 35, 4119, 11031, 4847, 11032, 4570, 7878, 27 ]
[ "Adolescent", "Adult", "Association", "Cues", "Female", "Humans", "Male", "Mental Recall", "Practice, Psychological", "Recognition, Psychology", "Repetition Priming", "Semantics", "Word Association Tests", "Young Adult" ]
{ "A": 0, "B": 1, "C": 0, "D": 0, "E": 0, "F": 1, "G": 0, "H": 0, "I": 0, "J": 0, "L": 1, "M": 1, "N": 0, "Z": 0 }
1189772
[Clinical experience with Dilatol therapy in EPH-gestoses].
An information about the experience with DILATOL-treatment of 11 patients suffering from EPH-gestosis with hypertonia as the main symptom, is given. In all cases it was possible to reduce the systolic and diastolic blood-pressure. In long-time treatment an increasing resistance to therapy was noticed. In any case the t...
[ 522, 136, 2, 682, 3, 229, 15305, 7132, 20, 5970, 1020 ]
[ "Blood Pressure", "Drug Evaluation", "Female", "Fetus", "Humans", "Infant, Newborn", "Nylidrin", "Pre-Eclampsia", "Pregnancy", "Pulse", "Vasodilator Agents" ]
{ "A": 1, "B": 1, "C": 1, "D": 1, "E": 1, "F": 0, "G": 1, "H": 0, "I": 0, "J": 0, "L": 0, "M": 1, "N": 0, "Z": 0 }
189915
Effect of prolactin on growth and the estrogen receptor level of human breast cancer cells (MCF-7).
The intracellular specific 17beta-estradiol binding in the human breast cancer cell line, MCF-7, was shown to be modified by prolactin. Both ovine and human prolactin doubled the estradiol receptor (E2R) level, but the latter was at least 10 times more stimulatory on a concentration basis. Most of the E2R complex (appr...
[ 1135, 388, 5739, 1503, 1331, 51, 2991, 2417, 1423, 1108, 765, 3, 698, 2452, 1427, 372, 5284, 1137 ]
[ "3',5'-Cyclic-AMP Phosphodiesterases", "Breast Neoplasms", "Bucladesine", "Cell Division", "Cell Nucleus", "Cells, Cultured", "Cyclic AMP", "Cytosol", "DNA, Neoplasm", "Drug Interactions", "Estradiol", "Humans", "Insulin", "Neoplasm Proteins", "Prolactin", "Protein Binding", "Recepto...
{ "A": 1, "B": 1, "C": 1, "D": 1, "E": 0, "F": 0, "G": 1, "H": 0, "I": 0, "J": 0, "L": 0, "M": 0, "N": 0, "Z": 0 }
25860209
Comparison of UHPLC and HPLC in benzodiazepines analysis of postmortem samples: a case-control study.
The aim of this study was to compare system efficiency and analysis duration regarding the solvent consumption and system maintenance in high-pressure liquid chromatography (HPLC) and ultra high-pressure liquid chromatography (UHPLC). In a case-control study, standard solutions of 7 benzodiazepines (BZs) and 73 biologi...
[ 410, 1573, 761, 626, 3 ]
[ "Autopsy", "Benzodiazepines", "Case-Control Studies", "Chromatography, High Pressure Liquid", "Humans" ]
{ "A": 0, "B": 1, "C": 0, "D": 1, "E": 1, "F": 0, "G": 0, "H": 0, "I": 1, "J": 0, "L": 0, "M": 0, "N": 1, "Z": 0 }
25059396
Direct and indirect effects of glomalin, mycorrhizal hyphae, and roots on aggregate stability in rhizosphere of trifoliate orange.
To test direct and indirect effects of glomalin, mycorrhizal hyphae, and roots on aggregate stability, perspex pots separated by 37-ìm nylon mesh in the middle were used to form root-free hyphae and root/hyphae chambers, where trifoliate orange (Poncirus trifoliata) seedlings were colonized by Funneliformis mosseae or ...
[ 5541, 10097, 2816, 12785, 8058, 1074, 17701, 9593, 8059 ]
[ "Fungal Proteins", "Glomeromycota", "Glycoproteins", "Hyphae", "Mycorrhizae", "Plant Roots", "Poncirus", "Rhizosphere", "Seedlings" ]
{ "A": 1, "B": 1, "C": 0, "D": 1, "E": 0, "F": 0, "G": 1, "H": 0, "I": 0, "J": 0, "L": 0, "M": 0, "N": 1, "Z": 0 }
25450143
Decrease of neocortical paired-pulse depression in GAERS and possible implication of gap junctions.
Thalamocortical slices are widely used to study thalamocortical relationships and absence epilepsy. However, it is still not known whether (1) intracortical synaptic transmission, in particular neocortical paired-pulse depression (PPD), is maintained in these slices and (2) whether PPD is altered in the Genetic Absence...
[ 30, 2265, 15517, 2365, 613, 147, 10184, 4778, 34, 15229, 8411, 245, 1722, 2808 ]
[ "Animals", "Anticonvulsants", "Carbenoxolone", "Cerebral Cortex", "Disease Models, Animal", "Electric Stimulation", "Epilepsy, Absence", "Gap Junctions", "In Vitro Techniques", "Neocortex", "Quinidine", "Rats, Wistar", "Species Specificity", "Synaptic Transmission" ]
{ "A": 1, "B": 1, "C": 1, "D": 1, "E": 1, "F": 0, "G": 1, "H": 0, "I": 0, "J": 0, "L": 0, "M": 0, "N": 0, "Z": 0 }
10979425
[Aortopexy for tracheomalacia in infants and children].
During the past 12 years (1985-1998), 28 infants and children were operated on here for tracheomalacia. The diagnosis was made in all using rigid bronchoscopy. During the examination the infants breathed spontaneously, but the trachea collapsed on forced expiration. Indications for surgery were repeated cyanotic spells...
[ 3439, 105, 3, 14, 229, 15126, 598, 11943 ]
[ "Aorta, Thoracic", "Child, Preschool", "Humans", "Infant", "Infant, Newborn", "Laryngeal Cartilages", "Retrospective Studies", "Tracheal Diseases" ]
{ "A": 1, "B": 1, "C": 1, "D": 0, "E": 1, "F": 0, "G": 0, "H": 0, "I": 0, "J": 0, "L": 0, "M": 1, "N": 1, "Z": 0 }
8958
Effects of chlorthalidone on serum and total body potassium in hypertensive patients.
Total body potassium has been estimated in 26 hypertensive patients who were hypokalaemic as a result of long-term chlorthalidone treatment (mean 20.5 months), while they were on chlorthalidone and 4 weeks after this had been discontinued. The mean difference amounted to only 95 mEq (not significant). In 6 additional p...
[ 9, 521, 862, 12164, 2166, 11039, 2, 3, 1707, 1312, 15934, 35, 160, 3594, 1860, 131 ]
[ "Adult", "Antihypertensive Agents", "Body Weight", "Chlorthalidone", "Drug Therapy, Combination", "Electrolytes", "Female", "Humans", "Hydrogen-Ion Concentration", "Hypertension", "Hypokalemia", "Male", "Middle Aged", "Potassium", "Potassium Chloride", "Time Factors" ]
{ "A": 0, "B": 1, "C": 1, "D": 1, "E": 1, "F": 0, "G": 1, "H": 0, "I": 0, "J": 0, "L": 0, "M": 1, "N": 0, "Z": 0 }
21907826
Statistical process control for validating a classification tree model for predicting mortality--a novel approach towards temporal validation.
Prediction models are postulated as useful tools to support tasks such as clinical decision making and benchmarking. In particular, classification tree models have enjoyed much interest in the Biomedical Informatics literature. However, their prospective predictive performance over the course of time has not been inves...
[ 133, 4629, 2, 3, 35, 2614, 2040, 397 ]
[ "Aged", "Critical Care", "Female", "Humans", "Male", "Models, Statistical", "Mortality", "Prognosis" ]
{ "A": 0, "B": 1, "C": 0, "D": 0, "E": 1, "F": 0, "G": 0, "H": 0, "I": 0, "J": 0, "L": 0, "M": 1, "N": 1, "Z": 0 }
25681298
Treatment Patterns and Health Resource Utilization Among Patients Diagnosed With Early Stage Resected Non-Small Cell Lung Cancer at US Community Oncology Practices.
UNLABELLED: Data on adjuvant therapy in resected non-small cell lung cancer (NSCLC) in routine practice are lacking in the United States. This retrospective observational database study included 609 community oncology patients with resected stage IB to IIIA NSCLC. Use of adjuvant therapy was 39.1% at disease stage IB a...
[ 1450, 11650, 1963, 5281, 1317, 1829, 11307, 6122, 5501, 10052, 3, 159, 1187, 1931, 6585, 10023, 598, 132 ]
[ "Antineoplastic Combined Chemotherapy Protocols", "Carboplatin", "Carcinoma, Non-Small-Cell Lung", "Chemotherapy, Adjuvant", "Cisplatin", "Combined Modality Therapy", "Community Health Centers", "Costs and Cost Analysis", "Electronic Health Records", "Health Resources", "Humans", "Lung Neoplas...
{ "A": 0, "B": 1, "C": 1, "D": 1, "E": 1, "F": 0, "G": 0, "H": 0, "I": 1, "J": 0, "L": 0, "M": 0, "N": 1, "Z": 1 }
2870813
Retention of a functional resact receptor in isolated sperm plasma membranes.
Resact, a peptide obtained from eggs, causes a change in the Mr, and a loss of 32P from a plasma membrane protein identified as guanylate cyclase. Here, a resact analog (125I-[Tyr1, Ser8] resact) was synthesized and shown to bind to isolated sperm membranes. Resact, but not speract, competed with the radiolabeled ligan...
[ 30, 2364, 283, 5412, 2377, 14808, 7476, 35, 285, 1532, 4271, 2453, 586, 5276, 2191, 1746 ]
[ "Animals", "Binding, Competitive", "Cell Membrane", "Chemotaxis", "Cyclic GMP", "Egg Proteins", "Guanylate Cyclase", "Male", "Membrane Proteins", "Molecular Weight", "Oligopeptides", "Peptides", "Phosphorylation", "Receptors, Cell Surface", "Sea Urchins", "Spermatozoa" ]
{ "A": 1, "B": 1, "C": 0, "D": 1, "E": 1, "F": 1, "G": 1, "H": 0, "I": 0, "J": 0, "L": 0, "M": 0, "N": 0, "Z": 0 }
19126257
Information technology capacities assessment tool in hospitals: instrument development and validation.
OBJECTIVES: This research integrates existing literature on information technology (IT) in hospitals, and proposes and validates a comprehensive IT capacities assessment tool in these settings.METHODS: A comprehensive literature review was conducted on Medline until September 2006 to identify studies that used specific...
[ 3143, 3590, 7039, 3, 4459, 4460, 97, 5451, 5704 ]
[ "Canada", "Health Care Surveys", "Hospital Information Systems", "Humans", "Ontario", "Quebec", "Reproducibility of Results", "Systems Integration", "Technology Assessment, Biomedical" ]
{ "A": 0, "B": 1, "C": 0, "D": 0, "E": 1, "F": 0, "G": 0, "H": 1, "I": 0, "J": 0, "L": 1, "M": 0, "N": 1, "Z": 1 }
27956013
Determination of buildup and dilution of wastewater effluent in shellfish growing waters through a modified application of super-position.
Since 1925, dilution analysis has been used to minimize pathogenic impacts to bivalve molluscan shellfish growing areas from treated wastewater effluent in the National Shellfish Sanitation Program (NSSP). For over twenty five years, the U.S. Food and Drug Administration (FDA) has recommended a minimum of 1000:1 diluti...
[ 30, 3200, 247, 4035, 6573, 2813, 3883 ]
[ "Animals", "Bivalvia", "Environmental Monitoring", "Sewage", "Shellfish", "Waste Disposal, Fluid", "Waste Water" ]
{ "A": 0, "B": 1, "C": 0, "D": 1, "E": 0, "F": 0, "G": 1, "H": 0, "I": 0, "J": 1, "L": 0, "M": 0, "N": 1, "Z": 0 }
8203266
Differential alpha-smooth muscle actin expression in a gastric epithelioid leiomyosarcoma in a 14 year old girl.
Leiomyosarcoma in childhood is very rare. This report describes the immunohistochemical study of a gastric epithelioid leiomyosarcoma in a 14 year old girl. Microscopically, the tumor showed two distinct histological patterns within the same tumor: small epithelioid cells forming a lobular pattern and spindle-shaped ce...
[ 281, 204, 2, 3, 3373, 39, 3779 ]
[ "Actins", "Adolescent", "Female", "Humans", "Leiomyosarcoma", "Muscle, Smooth", "Stomach Neoplasms" ]
{ "A": 1, "B": 1, "C": 1, "D": 1, "E": 0, "F": 0, "G": 0, "H": 0, "I": 0, "J": 0, "L": 0, "M": 1, "N": 0, "Z": 0 }
29357212
Case Report of Metronidazole-Induced Encephalopathy.
This report describes the case of an 83-year-old woman who was admitted to a hospitalist service with weakness and falls. She was transferred from an outside facility where she was treated with 3 courses of metronidazole for diagnosed Clostridium difficile colitis and presumed reoccurrences. Magnetic resonance imaging ...
[ 310, 2331, 1937, 5398, 7768, 2, 3, 188, 7426 ]
[ "Aged, 80 and over", "Anti-Infective Agents", "Brain Diseases", "Clostridium Infections", "Colitis", "Female", "Humans", "Magnetic Resonance Imaging", "Metronidazole" ]
{ "A": 0, "B": 1, "C": 1, "D": 1, "E": 1, "F": 0, "G": 0, "H": 0, "I": 0, "J": 0, "L": 0, "M": 1, "N": 0, "Z": 0 }
12380527
[Use of transcranial micropolarization in the treatment of tension headaches].
The study was made of effectiveness of transcranial micropolarization (TSMP) in the treatment of tension headache (TH). A course of TSMP was conducted in 33 TH patients. TSMP has relieved TH, anxiety, depression. Neither side effects nor complications occurred.
[ 204, 9, 5535, 487, 3, 15314, 144 ]
[ "Adolescent", "Adult", "Electric Stimulation Therapy", "Electroencephalography", "Humans", "Tension-Type Headache", "Treatment Outcome" ]
{ "A": 0, "B": 1, "C": 1, "D": 0, "E": 1, "F": 0, "G": 0, "H": 0, "I": 0, "J": 0, "L": 0, "M": 1, "N": 1, "Z": 0 }
26420025
Polyol-enhanced dispersive liquid-liquid microextraction coupled with gas chromatography and nitrogen phosphorous detection for the determination of organophosphorus pesticides from aqueous samples, fruit juices, and vegetables.
Polyol-enhanced dispersive liquid-liquid microextraction has been proposed for the extraction and preconcentration of some organophosphorus pesticides from different samples. In the present study, a high volume of an aqueous phase containing a polyol (sorbitol) is prepared and then a disperser solvent along with an ext...
[ 8954, 1398, 3165, 12075, 6655, 12140, 5685, 7792, 5577, 4126, 4493, 654 ]
[ "Chemistry Techniques, Analytical", "Chromatography, Gas", "Food Analysis", "Fruit and Vegetable Juices", "Limit of Detection", "Liquid Phase Microextraction", "Nitrogen", "Organophosphorus Compounds", "Pesticides", "Phosphorus", "Vegetables", "Water" ]
{ "A": 0, "B": 1, "C": 0, "D": 1, "E": 1, "F": 0, "G": 1, "H": 0, "I": 0, "J": 1, "L": 0, "M": 0, "N": 1, "Z": 0 }
23238531
Seasonal variation, weather and behavior in day-care children: a multilevel approach.
This study analyzes the effect of weather variables, such as solar radiation, indoor and outdoor air temperature, relative humidity and time spent outdoor, on the behavior of 2-year-old children and their affects across different seasons: winter, spring and summer. Participants were a group of 61 children (33 males and...
[ 4808, 4443, 105, 12418, 319, 2, 19347, 3, 1454, 35, 23, 12509 ]
[ "Aggression", "Child Behavior", "Child, Preschool", "Day Care, Medical", "Environment", "Female", "Frustration", "Humans", "Italy", "Male", "Seasons", "Weather" ]
{ "A": 0, "B": 1, "C": 0, "D": 0, "E": 1, "F": 1, "G": 1, "H": 0, "I": 0, "J": 0, "L": 0, "M": 1, "N": 1, "Z": 1 }
19136026
The impact of single and dual hydrothermal modifications on the molecular structure and physicochemical properties of normal corn starch.
Effect of single and dual hydrothermal modifications with annealing (ANN) and heat-moisture treatment (HMT) on molecular structure and physicochemical properties of corn starch was investigated. Normal corn starch was modified by ANN at 70% moisture at 50 degrees C for 24h and HMT at 30% moisture at 120 degrees C for 2...
[ 14155, 14156, 30, 1243, 2304, 10458, 1660, 2834, 3037, 7726, 653, 654, 2835 ]
[ "Amylopectin", "Amylose", "Animals", "Crystallization", "Enzymes", "Gelatin", "Hydrolysis", "Spectroscopy, Fourier Transform Infrared", "Starch", "Sus scrofa", "Temperature", "Water", "X-Ray Diffraction" ]
{ "A": 0, "B": 1, "C": 0, "D": 1, "E": 1, "F": 0, "G": 1, "H": 0, "I": 0, "J": 0, "L": 0, "M": 0, "N": 1, "Z": 0 }
3490962
Placental secretion of androgens in the rat.
In contrast to the human placenta, which does not secrete androgens, the rat placenta synthesizes significant amounts of these steroids. The purpose of this study was to determine why the rat placenta does not secrete androgens before day 12 of pregnancy, to ascertain whether the rat placenta secretes more androstenedi...
[ 11285, 5580, 7227, 30, 9216, 730, 2, 2102, 684, 20, 43, 9105, 758, 4595 ]
[ "Aldehyde-Lyases", "Androgens", "Androstenedione", "Animals", "Corpus Luteum", "Cytochrome P-450 Enzyme System", "Female", "Gestational Age", "Placenta", "Pregnancy", "Rats", "Steroid 17-alpha-Hydroxylase", "Substrate Specificity", "Testosterone" ]
{ "A": 1, "B": 1, "C": 0, "D": 1, "E": 0, "F": 0, "G": 1, "H": 0, "I": 0, "J": 0, "L": 0, "M": 0, "N": 0, "Z": 0 }
24686174
E3 ubiquitin ligase HOIP attenuates apoptotic cell death induced by cisplatin.
The genotoxin cisplatin is commonly used in chemotherapy to treat solid tumors, yet our understanding of the mechanism underlying the drug response is limited. In a focused siRNA screen, using an siRNA library targeting genes involved in ubiquitin and ubiquitin-like signaling, we identified the E3 ubiquitin ligase HOIP...
[ 71, 193, 1295, 1976, 1317, 195, 2, 5642, 783, 79, 3, 7053, 1286, 860, 588, 9054 ]
[ "Antineoplastic Agents", "Apoptosis", "Cell Cycle Checkpoints", "Cell Death", "Cisplatin", "DNA Damage", "Female", "HCT116 Cells", "HEK293 Cells", "HeLa Cells", "Humans", "MAP Kinase Kinase 4", "Ovarian Neoplasms", "RNA, Small Interfering", "Signal Transduction", "Ubiquitin-Protein Lig...
{ "A": 1, "B": 1, "C": 1, "D": 1, "E": 0, "F": 0, "G": 1, "H": 0, "I": 0, "J": 0, "L": 0, "M": 0, "N": 0, "Z": 0 }
20722723
Heterogeneity of the supramammillary-hippocampal pathways: evidence for a unique GABAergic neurotransmitter phenotype and regional differences.
The supramammillary nucleus (SuM) provides substantial projections to the hippocampal formation. This hypothalamic structure is involved in the regulation of hippocampal theta rhythm and therefore the control of hippocampal-dependent cognitive functions as well as emotional behavior. A major goal of this study was to c...
[ 30, 1855, 241, 35, 17333, 1752, 17334, 5794, 956, 3431, 43, 69, 5035 ]
[ "Animals", "Glutamic Acid", "Hippocampus", "Male", "Mammillary Bodies", "Neural Pathways", "Neuroanatomical Tract-Tracing Techniques", "Neurotransmitter Agents", "Phenotype", "Presynaptic Terminals", "Rats", "Rats, Sprague-Dawley", "gamma-Aminobutyric Acid" ]
{ "A": 1, "B": 1, "C": 0, "D": 1, "E": 1, "F": 0, "G": 1, "H": 0, "I": 0, "J": 0, "L": 0, "M": 0, "N": 0, "Z": 0 }
22258285
Unilateral hyperplasia of lamina and spinous process of C6 vertebra: case report.
We report a 20-year-old male patient who was admitted to our emergency clinic after a traffic accident and who suffered from neck pain. Radiographic examination of the cervical spine showed hypertrophy of the left lamina and hypertrophy and elongation of the left spinous process of the sixth cervical vertebra (C6). A c...
[ 3903, 9, 170, 3, 1098, 188, 35, 11722, 1099, 27 ]
[ "Accidents, Traffic", "Adult", "Cervical Vertebrae", "Humans", "Hyperplasia", "Magnetic Resonance Imaging", "Male", "Neck Pain", "Tomography, X-Ray Computed", "Young Adult" ]
{ "A": 1, "B": 1, "C": 1, "D": 0, "E": 1, "F": 0, "G": 0, "H": 0, "I": 0, "J": 0, "L": 0, "M": 1, "N": 1, "Z": 0 }
31622255
Add-on grade-ranking scale for assessing thrombotic risk in patients with ischemic heart disease and percutaneous coronary angioplasty.
OBJECTIVE: Introduction: The anticipation of the development of thrombotic complications in coronary angioplasty patients helps to prevent this dangerous complication. Development of the available informative scales on the basis of mathematical methods taking into account the main clinical and biochemical parameters si...
[ 3469, 1232, 1309, 3, 1237, 1889, 177, 314 ]
[ "Angioplasty, Balloon, Coronary", "Coronary Disease", "Diabetes Mellitus", "Humans", "Recurrence", "Risk Assessment", "Risk Factors", "Thrombosis" ]
{ "A": 0, "B": 1, "C": 1, "D": 0, "E": 1, "F": 0, "G": 0, "H": 0, "I": 0, "J": 0, "L": 0, "M": 0, "N": 1, "Z": 0 }
19651142
Structural and functional diversity of novel coronin 1C (CRN2) isoforms in muscle.
Coronin 1C (synonyms: coronin-3, CRN2), a WD40 repeat-containing protein involved in cellular actin dynamics, is ubiquitously expressed in human tissues. Here, we report on the identification and functional characterization of two novel coronin 1C isoforms, referred to as CRN2i2 and CRN2i3, which also associate with F-...
[ 281, 28, 439, 1703, 657, 6398, 3005, 3, 4, 8688, 37, 60, 5120, 503, 1428, 2821, 5443, 505, 635 ]
[ "Actins", "Amino Acid Sequence", "Base Sequence", "Binding Sites", "Cell Line", "Chromatin Immunoprecipitation", "Computational Biology", "Humans", "Immunohistochemistry", "Microfilament Proteins", "Molecular Sequence Data", "Muscle, Skeletal", "Myofibrils", "Neuromuscular Junction", "Pr...
{ "A": 1, "B": 1, "C": 0, "D": 1, "E": 1, "F": 0, "G": 1, "H": 1, "I": 0, "J": 0, "L": 1, "M": 0, "N": 0, "Z": 0 }
22163844
Applying Rprop neural network for the prediction of the mobile station location.
Wireless location is the function used to determine the mobile station (MS) location in a wireless cellular communications system. When it is very hard for the surrounding base stations (BSs) to detect a MS or the measurements contain large errors in non-line-of-sight (NLOS) environments, then one need to integrate all...
[ 87, 3, 2140, 9535 ]
[ "Algorithms", "Humans", "Neural Networks, Computer", "Wireless Technology" ]
{ "A": 0, "B": 1, "C": 0, "D": 0, "E": 0, "F": 0, "G": 1, "H": 0, "I": 0, "J": 0, "L": 1, "M": 0, "N": 0, "Z": 0 }
805206
Evidence for the involvement of the Ss protein of the mouse in the hemolytic complement system.
A significant within-strain correlation has been demonstrated between the levels of Ss and hemolytic complement (C) activity in two Ss-high strains. Mouse serum specifically depleted of Ss by absorption with F(ab')2 fragments of anti-Ss had negligible C activity. In control experiments, Ss-specific antigen-antibody com...
[ 30, 1372, 9328, 3480, 4930, 766, 767, 14872, 4350, 297, 35, 36, 2897, 772, 433 ]
[ "Animals", "Blood Proteins", "Complement Fixation Tests", "Complement System Proteins", "Hemolysis", "Immune Sera", "Immunodiffusion", "Immunogenetics", "Immunoglobulin Fab Fragments", "Immunoglobulin G", "Male", "Mice", "Mice, Inbred Strains", "Rabbits", "Serum Albumin, Bovine" ]
{ "A": 1, "B": 1, "C": 1, "D": 1, "E": 1, "F": 0, "G": 1, "H": 1, "I": 0, "J": 0, "L": 0, "M": 0, "N": 0, "Z": 0 }
23192547
Data mining in the MetaCyc family of pathway databases.
Pathway databases collect the bioreactions and molecular interactions that define the processes of life. The MetaCyc family of pathway databases consists of thousands of databases that were derived through computational inference of metabolic pathways from the MetaCyc pathway/genome database (PGDB). In some cases, thes...
[ 30, 1363, 3005, 12913, 2969, 352, 441, 7198, 1132, 10755, 6793, 6701, 3, 2209, 7699, 36, 1549, 3371, 1693 ]
[ "Animals", "Arabidopsis", "Computational Biology", "Data Mining", "Databases, Genetic", "Escherichia coli", "Gene Expression", "Gene Regulatory Networks", "Genome, Bacterial", "Genome, Fungal", "Genome, Human", "Genome, Plant", "Humans", "Internet", "Metabolic Networks and Pathways", "...
{ "A": 0, "B": 1, "C": 0, "D": 0, "E": 1, "F": 0, "G": 1, "H": 1, "I": 0, "J": 0, "L": 1, "M": 0, "N": 0, "Z": 0 }
23160439
Perceived suprathreshold depth under conditions that elevate the stereothreshold.
PURPOSE: Previous studies considered the possibility that individuals with impaired stereoacuity can be identified by estimating the perceived depth of a target with a suprathreshold retinal image disparity. These studies showed that perceived suprathreshold depth is reduced when the image presented to one eye is blurr...
[ 9, 4691, 2, 3, 35, 160, 1081, 11195, 9684, 999, 27 ]
[ "Adult", "Depth Perception", "Female", "Humans", "Male", "Middle Aged", "Sensory Thresholds", "Vision Disparity", "Vision, Binocular", "Visual Acuity", "Young Adult" ]
{ "A": 0, "B": 1, "C": 0, "D": 0, "E": 1, "F": 1, "G": 1, "H": 0, "I": 0, "J": 0, "L": 0, "M": 1, "N": 0, "Z": 0 }
16708424
Ultraviolet radiation increases the toxicity of pyrene, 1-aminopyrene and 1-hydroxypyrene to human keratinocytes.
Over the past several years, a great deal of interest has been focused on the harmful effects of ultraviolet (UV) radiation to human skin. UV light has been implicated in aging, sunburn and skin cancer. Few studies, however, have been done to determine the effects that UV light, in conjunction with other environmental ...
[ 657, 72, 3, 4560, 11833, 6602, 2383 ]
[ "Cell Line", "Cell Proliferation", "Humans", "Keratinocytes", "Pyrenes", "Thymidine", "Ultraviolet Rays" ]
{ "A": 1, "B": 1, "C": 0, "D": 1, "E": 0, "F": 0, "G": 1, "H": 0, "I": 0, "J": 0, "L": 0, "M": 0, "N": 1, "Z": 0 }
26395549
Dietary Oily Fish Intake and Blood Pressure Levels: A Population-Based Study.
The effect of fish consumption on blood pressure is controversial. The authors measured blood pressure and calculated oily fish servings per week in 677 community-dwellers aged 40 years and older living in rural coastal Ecuador. Using regression models with linear splines, the authors evaluated whether dietary fish int...
[ 9, 522, 3528, 13782, 13212, 2, 11172, 3, 1312, 35, 160, 1272, 1274, 1889, 177, 643 ]
[ "Adult", "Blood Pressure", "Blood Pressure Determination", "Dietary Fats, Unsaturated", "Ecuador", "Female", "Fish Oils", "Humans", "Hypertension", "Male", "Middle Aged", "Population Surveillance", "Prevalence", "Risk Assessment", "Risk Factors", "Rural Population" ]
{ "A": 0, "B": 1, "C": 1, "D": 1, "E": 1, "F": 0, "G": 1, "H": 0, "I": 0, "J": 1, "L": 0, "M": 1, "N": 1, "Z": 1 }
30700385
Thyrotoxicosis: an unusual cause of syncope.
Syncope is a common emergency department (ED) chief complaint, with many known but also unknown causes. Here we present a novel ED presentation of a young woman with new-onset hyperthyroidism that masqueraded as a syncopal event with head trauma. A 21-year-old woman arrived in the ED with head trauma as the result of s...
[ 8555, 7852, 207, 731, 2, 3, 15086, 10850, 12501, 9861, 18325, 27 ]
[ "Antithyroid Agents", "Craniocerebral Trauma", "Diagnosis, Differential", "Electrocardiography", "Female", "Humans", "Methimazole", "Syncope", "Tachycardia", "Thyroid Function Tests", "Thyrotoxicosis", "Young Adult" ]
{ "A": 0, "B": 1, "C": 1, "D": 1, "E": 1, "F": 0, "G": 0, "H": 0, "I": 0, "J": 0, "L": 0, "M": 1, "N": 0, "Z": 0 }
2029246
Vaccination of turkeys with cell-free culture filtrate of Pasteurella multocida.
Turkeys given cell-free culture filtrate (CCF) of Pasteurella multocida strain R44/6 orally, via air sacs, or subcutaneously mixed 1:1 with incomplete Freund's adjuvant (IFA) at 6 and 9.5 weeks of age were compared with negative controls given bacteriologic medium and positive controls vaccinated with a commercial bact...
[ 461, 4476, 30, 2142, 1353, 862, 2, 2077, 35, 15833, 14141, 5066, 417, 10081, 2783 ]
[ "Administration, Oral", "Air Sacs", "Animals", "Antibodies, Bacterial", "Bacterial Vaccines", "Body Weight", "Female", "Injections, Subcutaneous", "Male", "Pasteurella", "Pasteurella Infections", "Poultry Diseases", "Sex Factors", "Turkeys", "Vaccination" ]
{ "A": 1, "B": 1, "C": 1, "D": 1, "E": 1, "F": 0, "G": 1, "H": 0, "I": 0, "J": 0, "L": 0, "M": 0, "N": 1, "Z": 0 }
24976172
Bacterial sugar utilization gives rise to distinct single-cell behaviours.
Inducible utilization pathways reflect widespread microbial strategies to uptake and consume sugars from the environment. Despite their broad importance and extensive characterization, little is known how these pathways naturally respond to their inducing sugar in individual cells. Here, we performed single-cell analys...
[ 6469, 352, 1279, 7699, 1542, 9202 ]
[ "Carbohydrate Metabolism", "Escherichia coli", "Gene Expression Regulation, Bacterial", "Metabolic Networks and Pathways", "Models, Biological", "Single-Cell Analysis" ]
{ "A": 0, "B": 1, "C": 0, "D": 0, "E": 1, "F": 0, "G": 1, "H": 0, "I": 0, "J": 0, "L": 0, "M": 0, "N": 0, "Z": 0 }
12734819
Fiber-enriched double-setting calcium phosphate bone cement.
Calcium phosphate bone cements are useful in orthopedics and traumatology, their main advantages being their biocompatibility and bioactivity, which render bone tissue osteoconductive, providing in situ hardening and easy handling. However, their low mechanical strength, which, in the best of cases, is equal to the tra...
[ 48, 6091, 183, 4125, 3518, 52, 58, 1155, 10876, 7466, 3406 ]
[ "Biocompatible Materials", "Body Fluids", "Bone Cements", "Calcium Phosphates", "Carbon", "Compressive Strength", "Materials Testing", "Microscopy, Electron, Scanning", "Nylons", "Polypropylenes", "Tensile Strength" ]
{ "A": 1, "B": 0, "C": 0, "D": 1, "E": 1, "F": 0, "G": 1, "H": 0, "I": 0, "J": 1, "L": 0, "M": 0, "N": 0, "Z": 0 }
614533
The fine structure of intra-erythrocytic stages of Babesia bigemina.
The electron microscope was used to study the structure of merozoites, merozoites in the process of transformation to trophozoites, trophozoites, and the method of multiplication of B. bigemina. The merozoites were piriform in shape and surrounded by 3 peripheral membranes of which the 2 inner ones often appeared as a ...
[ 30, 4065, 9894, 424, 2174, 227, 35, 286 ]
[ "Animals", "Babesia", "Babesiosis", "Cattle", "Cattle Diseases", "Erythrocytes", "Male", "Microscopy, Electron" ]
{ "A": 1, "B": 1, "C": 1, "D": 0, "E": 1, "F": 0, "G": 0, "H": 0, "I": 0, "J": 0, "L": 0, "M": 0, "N": 0, "Z": 0 }
23189193
A proteomic analysis of seed development in Brassica campestri L.
To gain insights into the protein dynamics during seed development, a proteomic study on the developing Brassica campestri L. seeds with embryos in different embryogenesis stages was carried out. The seed proteins at 10, 16, 20, 25 and 35 DAP (days after pollination), respectively, were separated using two-dimensional ...
[ 9590, 2133, 2731, 3989, 3990, 2621 ]
[ "Brassica", "Cluster Analysis", "Plant Proteins", "Proteome", "Proteomics", "Seeds" ]
{ "A": 1, "B": 1, "C": 0, "D": 1, "E": 1, "F": 0, "G": 1, "H": 1, "I": 0, "J": 1, "L": 0, "M": 0, "N": 1, "Z": 0 }
23337664
A simple framework for assessing technical skills in a resident observed structured clinical examination (OSCE): vaginal laceration repair.
OBJECTIVES: Educators of trainees in procedure-based specialties need focused assessment tools that are valid, objective, and assess technical skills in a realistic context. A framework for hybrid assessment using standardized patient scenarios and bench skills testing might facilitate evaluation of competency.METHODS:...
[ 878, 3281, 1986, 9653, 2, 8418, 3, 6984, 12926, 8980, 4697 ]
[ "Clinical Competence", "Delivery, Obstetric", "Educational Measurement", "Episiotomy", "Female", "Gynecology", "Humans", "Lacerations", "Manikins", "Obstetrics", "Vagina" ]
{ "A": 1, "B": 1, "C": 1, "D": 0, "E": 1, "F": 0, "G": 0, "H": 1, "I": 1, "J": 1, "L": 1, "M": 0, "N": 1, "Z": 0 }
2613250
Heterogeneity in the biological and cultural determinants of high-density lipoprotein cholesterol in five North American populations: the Lipid Research Clinics Family Study.
Heterogeneity in the source of familial resemblance for high-density lipoprotein (HDL) cholesterol in 5 different Lipid Research Clinics (Cincinnati, Iowa, Minnesota, Oklahoma and Stanford) was assessed using a general linear model for cultural and biological inheritance. No evidence of heterogeneity was found in any o...
[ 4115, 319, 2, 219, 896, 3, 35, 1624, 956, 5334, 132 ]
[ "Cholesterol, HDL", "Environment", "Female", "Genetic Variation", "Genetics, Population", "Humans", "Male", "Models, Genetic", "Phenotype", "Statistics as Topic", "United States" ]
{ "A": 0, "B": 1, "C": 0, "D": 1, "E": 1, "F": 0, "G": 1, "H": 1, "I": 0, "J": 0, "L": 0, "M": 0, "N": 1, "Z": 1 }
15585138
Alcohol-mediated error-prone PCR.
The effect of urea, isopropanol, propan-1-ol, and butan-1-ol on PCR using three different DNA polymerases was investigated. In the presence of these agents, polymerases were active as expected up to a critical concentration where they became progressively inhibited. Critical concentrations of alcohols generally increas...
[ 20715, 7084, 439, 17847, 440, 449, 2968 ]
[ "1-Propanol", "2-Propanol", "Base Sequence", "Butanols", "DNA Primers", "Polymerase Chain Reaction", "Urea" ]
{ "A": 0, "B": 0, "C": 0, "D": 1, "E": 1, "F": 0, "G": 1, "H": 0, "I": 0, "J": 0, "L": 1, "M": 0, "N": 0, "Z": 0 }
23796533
Fast nonlinear region localisation for nonlinear dielectric spectroscopy of biological suspensions.
The nonlinear properties of biological suspensions have been previously presented as a bulk phenomenon without the influences of the electrodes. However, some authors have showed that the behaviour of a biological suspension is due to the nonlinear characteristics of the electrode-electrolyte interface (EEI), which is ...
[ 17479, 2152, 835, 97, 3371, 131 ]
[ "Dielectric Spectroscopy", "Fourier Analysis", "Nonlinear Dynamics", "Reproducibility of Results", "Saccharomyces cerevisiae", "Time Factors" ]
{ "A": 0, "B": 1, "C": 0, "D": 0, "E": 1, "F": 0, "G": 1, "H": 1, "I": 0, "J": 0, "L": 1, "M": 0, "N": 1, "Z": 0 }
3090717
An analysis of computed tomographic brain scans. A computer-based study.
A microcomputer was used to analyse prospectively 1,000 sequential computed tomographic (CT) brain scans to assess whether the scanner was being used in a cost-effective and efficient manner. Of the patients scanned 58% had cerebral lesions. All the usual indications for CT examination were shown to be worth while, the...
[ 204, 9, 133, 1937, 3075, 2406, 104, 105, 918, 2, 3, 14, 229, 35, 7027, 160, 1099 ]
[ "Adolescent", "Adult", "Aged", "Brain Diseases", "Brain Injuries", "Brain Neoplasms", "Child", "Child, Preschool", "Cost-Benefit Analysis", "Female", "Humans", "Infant", "Infant, Newborn", "Male", "Microcomputers", "Middle Aged", "Tomography, X-Ray Computed" ]
{ "A": 0, "B": 1, "C": 1, "D": 0, "E": 1, "F": 0, "G": 0, "H": 0, "I": 0, "J": 0, "L": 1, "M": 1, "N": 1, "Z": 0 }
22927102
Antifungal compounds from the rhizome and roots of Ferula hermonis.
The antifungal activity of hexane, dichloromethane, methanol and aqueous extracts from the rhizome and root of Ferula hermonis was assayed in vitro by the agar disk diffusion method against a panel of human opportunistic and pathogenic fungi. Among them, the hexane and dichloromethane extracts showed the highest activi...
[ 728, 15135, 3385, 9637, 5195, 3434, 19763, 1172, 9131, 743, 6265, 1074, 9165, 8350, 12000 ]
[ "Antifungal Agents", "Arthrodermataceae", "Benzoates", "Bridged Bicyclo Compounds", "Candida", "Cycloheptanes", "Ferula", "Microbial Sensitivity Tests", "Microsporum", "Plant Extracts", "Plant Oils", "Plant Roots", "Rhizome", "Sesquiterpenes", "Trichophyton" ]
{ "A": 1, "B": 1, "C": 0, "D": 1, "E": 1, "F": 0, "G": 0, "H": 0, "I": 0, "J": 0, "L": 0, "M": 0, "N": 0, "Z": 0 }
19931221
Characterization of zinc-binding properties of a novel imidase from Pseudomonas putida YZ-26.
The imidase from Pseudomonas putida YZ-26 consisting of 293-amino acid residues is a novel imidase with four subunits as the holo-enzyme and low molecular weight which is significantly different from known mammalian imidase. This study measured the zinc-binding properties of the imidase using inductively coupled plasma...
[ 6590, 439, 440, 777, 372, 957, 6908, 506, 703 ]
[ "Amidohydrolases", "Base Sequence", "DNA Primers", "Electrophoresis, Polyacrylamide Gel", "Protein Binding", "Protein Conformation", "Pseudomonas putida", "Recombinant Proteins", "Zinc" ]
{ "A": 0, "B": 1, "C": 0, "D": 1, "E": 1, "F": 0, "G": 1, "H": 0, "I": 0, "J": 0, "L": 1, "M": 0, "N": 0, "Z": 0 }
27061753
A 21-35 kDa Mixed Protein Component from Helicobacter pylori Activates Mast Cells Effectively in Chronic Spontaneous Urticaria.
BACKGROUND: Helicobacter pylori (H. pylori) seem to involve in the etiology of chronic spontaneous urticaria (CSU). But studies of the pathogenic mechanism are very little.METHODS: In this study, we detected the serum-specific anti-H. pylori IgG and IgE antibodies in 211 CSU and 137 normal subjects by enzyme-linked imm...
[ 204, 9, 133, 2142, 5088, 819, 657, 1978, 778, 2, 3778, 3, 4349, 297, 35, 1930, 10397, 160, 1532, 1336, 6174, 4639, 27 ]
[ "Adolescent", "Adult", "Aged", "Antibodies, Bacterial", "Antigens, Bacterial", "Bacterial Proteins", "Cell Line", "Chromatography, Liquid", "Enzyme-Linked Immunosorbent Assay", "Female", "Helicobacter pylori", "Humans", "Immunoglobulin E", "Immunoglobulin G", "Male", "Mass Spectrometry...
{ "A": 1, "B": 1, "C": 1, "D": 1, "E": 1, "F": 0, "G": 1, "H": 0, "I": 0, "J": 0, "L": 0, "M": 1, "N": 0, "Z": 0 }
7849031
Comparison of the refolding of hen lysozyme from dimethyl sulfoxide and guanidinium chloride.
The folding of hen egg white lysozyme is complex, involving parallel pathways and distinct folding domains [Radford, S.E., Dobson, C.M., & Evans, P.A. (1992) Nature 358, 302-307]. In the present work the refolding of this protein from two denatured states that have different conformational properties, one generated by ...
[ 30, 2904, 3631, 357, 17255, 2, 13779, 8164, 713, 3070, 7894, 1281, 718 ]
[ "Animals", "Chickens", "Circular Dichroism", "Dimethyl Sulfoxide", "Egg White", "Female", "Guanidine", "Guanidines", "Magnetic Resonance Spectroscopy", "Muramidase", "Protein Denaturation", "Protein Folding", "Protein Structure, Secondary" ]
{ "A": 0, "B": 1, "C": 0, "D": 1, "E": 1, "F": 0, "G": 1, "H": 0, "I": 0, "J": 1, "L": 0, "M": 0, "N": 0, "Z": 0 }
1735076
Extent of nasopharyngeal carcinoma involvement inside the nasopharynx. Lack of prognostic value on local control.
A study on the use of fiberscopic examination and multiple biopsy specimens taken from the nasopharynx in the assessment of the extent of nasopharyngeal carcinoma (NPC) involvement inside the nasopharynx found that the involvement often was more extensive than the detected with conventional methods. In the current stud...
[ 8055, 162, 5352, 3, 1850, 8174, 10526, 1249, 1187, 397, 111 ]
[ "Actuarial Analysis", "Endoscopy", "Fiber Optic Technology", "Humans", "Lymphatic Metastasis", "Nasopharyngeal Neoplasms", "Nasopharynx", "Neoplasm Invasiveness", "Neoplasm Staging", "Prognosis", "Prospective Studies" ]
{ "A": 1, "B": 1, "C": 1, "D": 0, "E": 1, "F": 0, "G": 0, "H": 1, "I": 0, "J": 0, "L": 0, "M": 0, "N": 1, "Z": 0 }
11003795
Acquired slow-channel syndrome.
We report the case of a 37-year-old man with clinical and electrophysiological features of hereditary slow-channel syndrome (SCS) and antibodies against acetylcholine receptors (AChR-Abs). He presented with weakness of shoulder and hand muscles. A supramaximal single stimulus to the motor nerves disclosed a double comp...
[ 9, 3, 35, 120, 11466, 892 ]
[ "Adult", "Humans", "Male", "Muscles", "Myasthenic Syndromes, Congenital", "Neural Conduction" ]
{ "A": 1, "B": 1, "C": 1, "D": 0, "E": 0, "F": 0, "G": 1, "H": 0, "I": 0, "J": 0, "L": 0, "M": 1, "N": 0, "Z": 0 }
20220321
ASL perfusion MRI predicts cognitive decline and conversion from MCI to dementia.
We compared the predictive value of cerebral perfusion as measured by arterial-spin labeling magnetic resonance imaging (ASL-MRI) with MRI-derived hippocampal volume for determining future cognitive and functional decline and subsequent conversion from mild cognitive impairment to dementia. Forty-eight mild cognitive i...
[ 133, 206, 2721, 2645, 412, 2439, 2, 3, 188, 35, 1269, 365 ]
[ "Aged", "Brain", "Cerebrovascular Circulation", "Cognition Disorders", "Dementia", "Disease Progression", "Female", "Humans", "Magnetic Resonance Imaging", "Male", "Predictive Value of Tests", "Spin Labels" ]
{ "A": 1, "B": 1, "C": 1, "D": 1, "E": 1, "F": 1, "G": 1, "H": 0, "I": 0, "J": 0, "L": 0, "M": 1, "N": 1, "Z": 0 }
32692000
Analysis of clinical characteristics and outcomes in patients with COVID-19 based on a series of 1000 patients treated in Spanish emergency departments.
OBJECTIVES: To describe the clinical characteristics of patients with coronavirus disease 2019 (COVID-19) treated in hospital emergency departments (EDs) in Spain, and to assess associations between characteristics and outcomes.MATERIAL AND METHODS: Prospective, multicenter, nested-cohort study. Sixty-one EDs included ...
[ 204, 9, 906, 1402, 133, 310, 9435, 5216, 2860, 104, 105, 982, 1534, 254, 2, 3446, 3, 14, 229, 3677, 1270, 35, 160, 429, 596, 538, 5218, 5219, 397, 111, 9254, 152, 9436, 1962, 1347, 8492, 27 ]
[ "Adolescent", "Adult", "Age Distribution", "Age Factors", "Aged", "Aged, 80 and over", "Betacoronavirus", "COVID-19", "Cardiovascular Diseases", "Child", "Child, Preschool", "Comorbidity", "Coronavirus Infections", "Emergency Service, Hospital", "Female", "Hospital Mortality", "Human...
{ "A": 0, "B": 1, "C": 1, "D": 0, "E": 1, "F": 0, "G": 1, "H": 0, "I": 1, "J": 0, "L": 0, "M": 1, "N": 1, "Z": 1 }
21336861
Cadmium, lead and zinc concentrations in water, sediment and oyster (Crassostrea virginica) of San Andres Lagoon, Mexico.
The spatial distribution of cadmium, lead and zinc concentrations in water, sediment and oysters from San Andres Lagoon was evaluated. Significantly higher cadmium (0.33 mg L(-1)) and lead (0.70 mg L(-1)) concentrations in water were observed in front of the mouth of Tigre river, whereas, zinc concentration (5.0 mg L(-...
[ 30, 1139, 3307, 247, 543, 2387, 3308, 3309, 326, 703 ]
[ "Animals", "Cadmium", "Crassostrea", "Environmental Monitoring", "Geologic Sediments", "Lead", "Mexico", "Seawater", "Water Pollutants, Chemical", "Zinc" ]
{ "A": 0, "B": 1, "C": 0, "D": 1, "E": 0, "F": 0, "G": 1, "H": 0, "I": 0, "J": 0, "L": 0, "M": 0, "N": 1, "Z": 1 }
18724729
Coexistence of three specialist aphids on common milkweed, Asclepias syriaca.
Coexistence of host-specific herbivores on plants is believed to be governed by interspecific interactions, but few empirical studies have systematically unraveled these dynamics. We investigated the role of several factors in promoting coexistence among the aphids Aphis nerii, Aphis asclepiadis, and Myzocallis asclepi...
[ 30, 6693, 3126, 7706, 1379, 3215, 3970, 1722, 1687 ]
[ "Animals", "Ants", "Aphids", "Asclepias", "Feeding Behavior", "Host-Parasite Interactions", "Predatory Behavior", "Species Specificity", "Spiders" ]
{ "A": 0, "B": 1, "C": 0, "D": 0, "E": 0, "F": 1, "G": 1, "H": 0, "I": 0, "J": 0, "L": 0, "M": 0, "N": 0, "Z": 0 }
10848825
Re-exposure to recombinant (r)-hirudin in antihirudin antibody-positive patients with a history of heparin-induced thrombocytopenia.
Patients with a history of heparin-induced thrombocytopenia (HIT) and antibodies to hirudin were re-exposed to recombinant (r)-hirudin for prophylaxis of thromboembolism. Four patients were re-exposed to 2 x 25 mg of subcutaneous r-hirudin for 8-27 d. Two patients were re-exposed once, one patient twice and one four ti...
[ 9, 133, 3708, 1770, 2, 904, 11782, 10324, 3, 289, 297, 35, 160, 506, 2883, 8439, 905 ]
[ "Adult", "Aged", "Antibodies", "Anticoagulants", "Female", "Heparin", "Hirudin Therapy", "Hirudins", "Humans", "Immunoglobulin A", "Immunoglobulin G", "Male", "Middle Aged", "Recombinant Proteins", "Thrombocytopenia", "Thromboembolism", "Whole Blood Coagulation Time" ]
{ "A": 0, "B": 1, "C": 1, "D": 1, "E": 1, "F": 0, "G": 1, "H": 0, "I": 0, "J": 0, "L": 0, "M": 1, "N": 0, "Z": 0 }
964964
Operational dimensions of one multihospital system.
The pressing realities of health care delivery in the 1970s call for new solutions and fresh approaches to health care administration. The Lutheran Hospitals and Homes Society of America was founded to assist communities that were encountering difficulties in providing for the health care needs of their people. This ar...
[ 11696, 2994, 802, 3663, 11432, 132 ]
[ "Facility Design and Construction", "Hospital Administration", "Methods", "Nursing Homes", "Societies", "United States" ]
{ "A": 0, "B": 0, "C": 0, "D": 0, "E": 1, "F": 0, "G": 0, "H": 1, "I": 0, "J": 1, "L": 0, "M": 0, "N": 1, "Z": 1 }
15675620
[Liver and splenic sarcoidosis: diagnostic procedures].
INTRODUCTION: Clinical studies indicate involvement of the liver and spleen in approximately 20-30% of patients affected with sarcoidosis and their detection should be based on a standardized diagnostic procedure.DIAGNOSTIC PROCEDURES: Ultrasonography is a reliable and safe method to assess changes related to size and ...
[ 9, 133, 310, 2, 3, 1788, 35, 160, 1560, 18857 ]
[ "Adult", "Aged", "Aged, 80 and over", "Female", "Humans", "Liver Diseases", "Male", "Middle Aged", "Sarcoidosis", "Splenic Diseases" ]
{ "A": 0, "B": 1, "C": 1, "D": 0, "E": 0, "F": 0, "G": 0, "H": 0, "I": 0, "J": 0, "L": 0, "M": 1, "N": 0, "Z": 0 }
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PubMed MultiLabel Text Classification (MeSH)

A dataset of 50,000 PubMed biomedical articles, each manually annotated by domain experts with MeSH (Medical Subject Headings) labels. With 21,918 unique labels and a mean of ~12.7 labels per document, this is a densely-labeled extreme multi-label classification benchmark.

Dataset Description

Property Value
Train examples 40,000
Test examples 10,000
Total unique MeSH labels 21,918
Mean labels per document ~12.7
Median labels per document 12
Max labels per document 46

Label distribution

Docs per label # Labels % of total
1 3,990 18.2%
2–5 7,020 32.0%
6–10 3,412 15.6%
11–50 5,518 25.2%
51–100 1,068 4.9%
101+ 910 4.2%

MeSH Root Categories

Each label belongs to one or more MeSH root categories. The dataset includes binary indicator columns for the 14 root categories:

Code Root Category
A Anatomy
B Organisms
C Diseases
D Chemicals and Drugs
E Analytical, Diagnostic and Therapeutic Techniques, and Equipment
F Psychiatry and Psychology
G Phenomena and Processes
H Disciplines and Occupations
I Anthropology, Education, Sociology, and Social Phenomena
J Technology, Industry, and Agriculture
L Information Science
M Named Groups
N Health Care
Z Geographicals

Fields

Field Type Description
pmid string PubMed article ID
title string Article title
abstract string Article abstract text
label_ids list[int] MeSH label indices (into the 21,918-label vocabulary)
label_names list[string] Human-readable MeSH label names
mesh_roots dict Binary flags {"A": 0/1, ..., "Z": 0/1} for root categories

Additional files

  • label_vocab.json — ordered list of all 21,918 MeSH label names (index = label ID)
  • label_metadata.jsonl — full label metadata including MeSH tree IDs and root categories for hierarchical classification research

Splits

An 80/20 random split with seed 42 (no predefined split exists in the original data).

Usage

from datasets import load_dataset

ds = load_dataset("Tellurio/PubMed-MultiLabel-MeSH")

example = ds["train"][0]
print(example["title"])
print(example["label_names"])  # e.g. ["Humans", "Female", "DNA Probes, HPV", ...]
print(example["label_ids"])    # e.g. [5, 2, 0, ...]
print(example["mesh_roots"])   # e.g. {"A": 0, "B": 1, "C": 1, ...}

Loading label metadata for hierarchical / zero-shot approaches

Each of the 21,918 MeSH labels has associated tree IDs and root categories stored in label_metadata.jsonl.

import json
from huggingface_hub import hf_hub_download

path = hf_hub_download(
    repo_id="Tellurio/PubMed-MultiLabel-MeSH",
    filename="label_metadata.jsonl",
    repo_type="dataset",
)

labels = []
with open(path) as f:
    for line in f:
        labels.append(json.loads(line))

# Example label entry
print(labels[0])
# {"id": 0, "label": "DNA Probes, HPV", "mesh_tree_ids": ["D13.444...", ...], "mesh_roots": ["Chemicals and Drugs [D]"]}

Source

Originally from Kaggle: PubMed MultiLabel Text Classification Dataset MeSH by Owais Ahmad.

Citation

@misc{pubmed_multilabel_mesh,
  author = {Owais Ahmad},
  title = {PubMed MultiLabel Text Classification Dataset MeSH},
  year = {2022},
  publisher = {Kaggle},
  url = {https://www.kaggle.com/datasets/owaiskhan9654/pubmed-multilabel-text-classification}
}

License

CC0: Public Domain

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