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Do mitochondria play a role in remodelling lace plant leaves during programmed cell death?
[ "Programmed cell death (PCD) is the regulated death of cells within an organism. The lace plant (Aponogeton madagascariensis) produces perforations in its leaves through PCD. The leaves of the plant consist of a latticework of longitudinal and transverse veins enclosing areoles. PCD occurs in the cells at the cente...
[ "ANGUSTIFOLIA (AN), one of the CtBP family proteins, plays a major role in microtubule-dependent cell morphogenesis. Microarray analysis of mammalian AN homologs suggests that AN might function as a transcriptional activator and regulator of a wide range of genes. Genetic characterization of AN mutants suggests tha...
pubmedqa
{ "query": "Represent the Biomedical query for retrieving relevant passages:", "pos": "Represent the Biomedical passage for retrieval:", "neg": "Represent the Biomedical passage for retrieval:" }
Landolt C and snellen e acuity: differences in strabismus amblyopia?
[ "Assessment of visual acuity depends on the optotypes used for measurement. The ability to recognize different optotypes differs even if their critical details appear under the same visual angle. Since optotypes are evaluated on individuals with good visual acuity and without eye disorders, differences in the lower...
[ "To measure critical (foveal) flicker fusion frequencies (CFF) in normal eyes, unilateral maculopathies and neuropathies and in orthoptic amblyopias. A newly developed apparatus (4F) with LED's measured subjective foveal CFF by ascending and descending mode in a group of normals and patients. The apparatus (4F) mea...
pubmedqa
{ "query": "Represent the Biomedical question for retrieving relevant passages:", "pos": "Represent the Biomedical passage for retrieval:", "neg": "Represent the Biomedical passage for retrieval:" }
Syncope during bathing in infants, a pediatric form of water-induced urticaria?
[ "Apparent life-threatening events in infants are a difficult and frequent problem in pediatric practice. The prognosis is uncertain because of risk of sudden infant death syndrome. Eight infants aged 2 to 15 months were admitted during a period of 6 years; they suffered from similar maladies in the bath: on immersi...
[ "Although the commonest form of hypokalemic paralysis is the hereditary variety, some patients during course of thyrotoxicosis or with chronic potassium depletion, may exhibit episodic weakness. Approach to the patient with hypokalemic paralysis should be a careful search for the etiology and potassium replacement ...
pubmedqa
{ "query": "Represent the Biomedical query for retrieving relevant paragraphs:", "pos": "Represent the Biomedical paragraph for retrieval:", "neg": "Represent the Biomedical paragraph for retrieval:" }
Are the long-term results of the transanal pull-through equal to those of the transabdominal pull-through?
[ "The transanal endorectal pull-through (TERPT) is becoming the most popular procedure in the treatment of Hirschsprung disease (HD), but overstretching of the anal sphincters remains a critical issue that may impact the continence. This study examined the long-term outcome of TERPT versus conventional transabdomina...
[ "The surgical procedure for treating congenital duodenal atresia has normally been performed by an upper abdominal transverse incision. Recently, duodenoduodenostomy has been attempted using an umbilical crease incision to improve the cosmetic results. Eighteen cases of duodenal obstruction, including 15 atresia, 2...
pubmedqa
{ "query": "Represent the Biomedical query for retrieving relevant paragraphs:", "pos": "Represent the Biomedical paragraph for retrieval:", "neg": "Represent the Biomedical paragraph for retrieval:" }
Can tailored interventions increase mammography use among HMO women?
[ "Telephone counseling and tailored print communications have emerged as promising methods for promoting mammography screening. However, there has been little research testing, within the same randomized field trial, of the efficacy of these two methods compared to a high-quality usual care system for enhancing scre...
[ "Low adherence to cervical and breast cancer (CBC) screening recommendations contributes to high CBC mortality among Latinas. To estimate the prevalence of, and factors associated with, last 12-month Pap smear and mammogram receipt among a Midwest community sample of low-acculturated Latinas. We conducted a cross-s...
pubmedqa
{ "query": "Represent the Biomedical query for retrieving relevant paragraphs:", "pos": "Represent the Biomedical paragraph for retrieval:", "neg": "Represent the Biomedical paragraph for retrieval:" }
Double balloon enteroscopy: is it efficacious and safe in a community setting?
[ "From March 2007 to January 2011, 88 DBE procedures were performed on 66 patients. Indications included evaluation anemia/gastrointestinal bleed, small bowel IBD and dilation of strictures. Video-capsule endoscopy (VCE) was used prior to DBE in 43 of the 66 patients prior to DBE evaluation. The mean age was 62 year...
[ "The aim of this study was to investigate the outcome of endoluminal stenting in the management of patients presenting with acute large bowel obstruction. Twenty-eight consecutive patients presenting to one consultant surgeon with large bowel obstruction were considered for the procedure. Twenty-four patients were ...
pubmedqa
{ "query": "Represent the Biomedical query for retrieving relevant paragraphs:", "pos": "Represent the Biomedical paragraph for retrieval:", "neg": "Represent the Biomedical paragraph for retrieval:" }
30-Day and 1-year mortality in emergency general surgery laparotomies: an area of concern and need for improvement?
[ "Emergency surgery is associated with poorer outcomes and higher mortality with recent studies suggesting the 30-day mortality to be 14-15%. The aim of this study was to analyse the 30-day mortality, age-related 30-day mortality and 1-year mortality following emergency laparotomy. We hope this will encourage prospe...
[ "Abdominal aortic aneurysm repair is associated with significant morbidity and mortality. This study aims to evaluate the efficiency of scoring systems in a group of patients undergoing abdominal aortic aneurysm repair. A prospective study of 152 patients undergoing aneurysm repair was conducted. Each patient was s...
pubmedqa
{ "query": "Represent the Biomedical question for retrieving relevant documents:", "pos": "Represent the Biomedical document for retrieval:", "neg": "Represent the Biomedical document for retrieval:" }
Is adjustment for reporting heterogeneity necessary in sleep disorders?
[ "Anchoring vignettes are brief texts describing a hypothetical character who illustrates a certain fixed level of a trait under evaluation. This research uses vignettes to elucidate factors associated with sleep disorders in adult Japanese before and after adjustment for reporting heterogeneity in self-reports. Thi...
[ "To accommodate and correct identifiable bias and risks of bias among clinical trials of nicotine replacement therapy (NRT). Meta-regression analysis of a published Cochrane Collaboration systematic review of 122 placebo-controlled clinical trials. Both identified risks of bias and potential publication (or reporti...
pubmedqa
{ "query": "Represent the Biomedical question for retrieving relevant paragraphs:", "pos": "Represent the Biomedical paragraph for retrieval:", "neg": "Represent the Biomedical paragraph for retrieval:" }
Do mutations causing low HDL-C promote increased carotid intima-media thickness?
[ "Although observational data support an inverse relationship between high-density lipoprotein (HDL) cholesterol and coronary heart disease (CHD), genetic HDL deficiency states often do not correlate with premature CHD. Carotid intima-media thickness (cIMT) measurements were obtained in cases comprising 10 different...
[ "Circulating oxidized low-density lipoprotein (LDL) has been shown to be a useful marker for identifying patients with coronary heart disease (CHD) and persons at high cardiovascular risk. The effect of cholesterol-lowering therapy on plasma level of oxidized LDL is not clear. We investigated effects of cholesterol...
pubmedqa
{ "query": "Represent the Biomedical query for retrieving relevant passages:", "pos": "Represent the Biomedical passage for retrieval:", "neg": "Represent the Biomedical passage for retrieval:" }
A short stay or 23-hour ward in a general and academic children's hospital: are they effective?
[ "We evaluated the usefulness of a short stay or 23-hour ward in a pediatric unit of a large teaching hospital, Westmead Hospital, and an academic Children's hospital, The New Children's Hospital, to determine if they are a useful addition to the emergency service. This is a descriptive comparison of prospectively c...
[ "To evaluate the effectiveness of the role of a discharge coordinator whose sole responsibility was to plan and coordinate the discharge of patients from medical wards. An intervention study in which the quality of discharge planning was assessed before and after the introduction of a discharge coordinator. Patient...
pubmedqa
{ "query": "Represent the Biomedical query for retrieving relevant passages:", "pos": "Represent the Biomedical passage for retrieval:", "neg": "Represent the Biomedical passage for retrieval:" }
Did Chile's traffic law reform push police enforcement?
[ "The objective of the current study is to determine to what extent the reduction of Chile's traffic fatalities and injuries during 2000-2012 was related to the police traffic enforcement increment registered after the introduction of its 2005 traffic law reform. A unique dataset with assembled information from publ...
[ "In 1994, Arizona voters approved Proposition 200 which increased the tobacco tax and earmarked 23% of the new revenues for tobacco education programmes. To describe the campaign to pass Proposition 200, the legislative debate that followed the passage of the initiative, and the development and implementation of th...
pubmedqa
{ "query": "Represent the Biomedical question for retrieving relevant passages:", "pos": "Represent the Biomedical passage for retrieval:", "neg": "Represent the Biomedical passage for retrieval:" }
Therapeutic anticoagulation in the trauma patient: is it safe?
[ "Trauma patients who require therapeutic anticoagulation pose a difficult treatment problem. The purpose of this study was to determine: (1) the incidence of complications using therapeutic anticoagulation in trauma patients, and (2) if any patient factors are associated with these complications. An 18-month retros...
[ "To evaluate data addressing use of anticoagulation in elderly patients with atrial fibrillation (AF), in particular those at risk of falls. Primary literature was identified through PubMed MEDLINE (1966-December 2007) and EMBASE (1980-December 2007) using the search terms anticoagulation, warfarin, aspirin, elderl...
pubmedqa
{ "query": "Represent the Biomedical question for retrieving relevant paragraphs:", "pos": "Represent the Biomedical paragraph for retrieval:", "neg": "Represent the Biomedical paragraph for retrieval:" }
Differentiation of nonalcoholic from alcoholic steatohepatitis: are routine laboratory markers useful?
[ "Specific markers for differentiation of nonalcoholic (NASH) from alcoholic steatohepatitis (ASH) are lacking. We investigated the role of routine laboratory parameters in distinguishing NASH from ASH. Liver biopsies performed at our hospital over a 10-year period were reviewed, 95 patients with steatohepatitis ide...
[ "Hepatic encephalopathy is a frequent complication of cirrhosis. The present retrospective investigation was conducted to characterize metabolic alterations in cirrhotic patients with and without hepatic encephalopathy. We tested the hypothesis that reduced nutritional status or the degree of tissue catabolism are ...
pubmedqa
{ "query": "Represent the Biomedical query for retrieving relevant paragraphs:", "pos": "Represent the Biomedical paragraph for retrieval:", "neg": "Represent the Biomedical paragraph for retrieval:" }
Prompting Primary Care Providers about Increased Patient Risk As a Result of Family History: Does It Work?
[ "Electronic health records have the potential to facilitate family history use by primary care physicians (PCPs) to provide personalized care. The objective of this study was to determine whether automated, at-the-visit tailored prompts about family history risk change PCP behavior. Automated, tailored prompts high...
[ "Parents often accompany adolescent and young adult (AYA) pediatric cancer survivors to follow-up oncology clinic visits and remain involved in their care, although little is known about their reasons for doing so. This mixed methods (qualitative-quantitative) study of 76 mothers of AYA survivors of childhood cance...
pubmedqa
{ "query": "Represent the Biomedical query for retrieving relevant paragraphs:", "pos": "Represent the Biomedical paragraph for retrieval:", "neg": "Represent the Biomedical paragraph for retrieval:" }
Do emergency ultrasound fellowship programs impact emergency medicine residents' ultrasound education?
[ "Recent years have seen a rapid proliferation of emergency ultrasound (EUS) programs in the United States. To date, there is no evidence supporting that EUS fellowships enhance residents' ultrasound (US) educational experiences. The purpose of this study was to determine the impact of EUS fellowships on emergency m...
[ "Surgical residents typically receive limited exposure to business and practice management during their training. As a result, residents are ill-prepared for issues related to starting a practice, coding, collecting, and taking a meaningful role within the medical community in promoting quality and safety and in co...
pubmedqa
{ "query": "Represent the Biomedical query for retrieving relevant documents:", "pos": "Represent the Biomedical document for retrieval:", "neg": "Represent the Biomedical document for retrieval:" }
Patient-Controlled Therapy of Breathlessness in Palliative Care: A New Therapeutic Concept for Opioid Administration?
[ "Breathlessness is one of the most distressing symptoms experienced by patients with advanced cancer and noncancer diagnoses alike. Often, severity of breathlessness increases quickly, calling for rapid symptom control. Oral, buccal, and parenteral routes of provider-controlled drug administration have been describ...
[ "To revise the South African Guideline for the Management of Chronic Obstructive Pulmonary Disease (COPD) based on emerging research that has informed updated recommendations." ]
pubmedqa
{ "query": "Represent the Biomedical question for retrieving relevant documents:", "pos": "Represent the Biomedical document for retrieval:", "neg": "Represent the Biomedical document for retrieval:" }
Is there still a need for living-related liver transplantation in children?
[ "To assess and compare the value of split-liver transplantation (SLT) and living-related liver transplantation (LRT). The concept of SLT results from the development of reduced-size transplantation. A further development of SLT, the in situ split technique, is derived from LRT, which itself marks the optimized outc...
[ "Kidney transplantation is generally regarded as the best treatment option for patients with end-stage renal disease. Because of an increase in the elderly population, the number of elderly patients with end-stage renal disease is expected to increase. The scope of this paper is to present existing knowledge about ...
pubmedqa
{ "query": "Represent the Biomedical question for retrieving relevant paragraphs:", "pos": "Represent the Biomedical paragraph for retrieval:", "neg": "Represent the Biomedical paragraph for retrieval:" }
Do patterns of knowledge and attitudes exist among unvaccinated seniors?
[ "To examine patterns of knowledge and attitudes among adults aged>65 years unvaccinated for influenza. Surveyed Medicare beneficiaries in 5 areas; clustered unvaccinated seniors by their immunization related knowledge and attitudes. Identified 4 clusters: Potentials (45%) would receive influenza vaccine to prevent ...
[ "AIDS is still a major cause of death. To combat this disease, researchers are developing a vaccine. Although blacks account for most new infections in the United States, they account for a low percent of experimental vaccine recipients. This study, conducted in a mid-sized U.S. city where vaccine trials are held, ...
pubmedqa
{ "query": "Represent the Biomedical question for retrieving relevant paragraphs:", "pos": "Represent the Biomedical paragraph for retrieval:", "neg": "Represent the Biomedical paragraph for retrieval:" }
Is there a model to teach and practice retroperitoneoscopic nephrectomy?
[ "Although the retroperitoneal approach has been the preferred choice for open urological procedures, retroperitoneoscopy is not the preferred approach for laparoscopy. This study aims to develop a training model for retroperitoneoscopy and to establish an experimental learning curve. Fifteen piglets were operated o...
[ "Natural orifice specimen extraction (NOSE) is an ever-evolving advanced laparoscopic technique. NOSE minimizes surgical injury, involving a low risk of wound complications, fewer incisional hernias, faster recovery and less postoperative pain. Laparoscopic gastrectomy combined with NOSE is a procedure that can pot...
pubmedqa
{ "query": "Represent the Biomedical question for retrieving relevant documents:", "pos": "Represent the Biomedical document for retrieval:", "neg": "Represent the Biomedical document for retrieval:" }
Cardiovascular risk in a rural adult West African population: is resting heart rate also relevant?
[ "Elevated resting heart rate (RHR) is a neglected marker in cardiovascular risk factor studies of sub-Saharan African populations. This study aimed to determine the prevalence of elevated RHR and other risk factors for cardiovascular disease (CVD) and to investigate any associations between RHR and these risk facto...
[ "Is intake of fatty acids related to semen quality among young men?" ]
pubmedqa
{ "query": "Represent the Biomedical query for retrieving relevant paragraphs:", "pos": "Represent the Biomedical paragraph for retrieval:", "neg": "Represent the Biomedical paragraph for retrieval:" }
Israeli hospital preparedness for terrorism-related multiple casualty incidents: can the surge capacity and injury severity distribution be better predicted?
[ "The incidence of large-scale urban attacks on civilian populations has significantly increased across the globe over the past decade. These incidents often result in Hospital Multiple Casualty Incidents (HMCI), which are very challenging to hospital teams. 15 years ago the Emergency and Disaster Medicine Division ...
[ "There are many reasons for the development of patient pathways in burn surgery introduced at the Royal Adelaide Hospital in South Australia at the beginning of January 2005. These include education, standardization of technique, scheduling of surgical episodes and rationalization of the use of expensive therapies....
pubmedqa
{ "query": "Represent the Biomedical question for retrieving relevant passages:", "pos": "Represent the Biomedical passage for retrieval:", "neg": "Represent the Biomedical passage for retrieval:" }
Acute respiratory distress syndrome in children with malignancy--can we predict outcome?
[ "The purpose of this study was to delineate early respiratory predictors of mortality in children with hemato-oncology malignancy who developed acute respiratory distress syndrome (ARDS). We conducted a retrospective chart review of children with malignant and ARDS who needed mechanical ventilation and were admitte...
[ "Sepsis is a leading cause of acute lung injury (ALI); however, the characteristics and outcome of sepsis-associated ALI are poorly understood. We aimed to elucidate factors that predict patient outcome in sepsis-associated ALI. Secondary analysis of a multicenter, prospective, observational study was performed. Am...
pubmedqa
{ "query": "Represent the Biomedical question for retrieving relevant documents:", "pos": "Represent the Biomedical document for retrieval:", "neg": "Represent the Biomedical document for retrieval:" }
Secondhand smoke risk in infants discharged from an NICU: potential for significant health disparities?
[ "Secondhand smoke exposure (SHSe) threatens fragile infants discharged from a neonatal intensive care unit (NICU). Smoking practices were examined in families with a high respiratory risk infant (born at very low birth weight; ventilated>12 hr) in a Houston, Texas, NICU. Socioeconomic status, race, and mental healt...
[ "Even though the prevalence of tobacco smoking has declined in the general population and among white-collar workers, the prevalence of tobacco smoking among blue-collar workers remains unacceptably high. Blue-collar workers experience greater exposure to workplace toxins which can add to, or even multiply, their r...
pubmedqa
{ "query": "Represent the Biomedical query for retrieving relevant documents:", "pos": "Represent the Biomedical document for retrieval:", "neg": "Represent the Biomedical document for retrieval:" }
Do nomograms designed to predict biochemical recurrence (BCR) do a better job of predicting more clinically relevant prostate cancer outcomes than BCR?
[ "To examine the ability of various postoperative nomograms to predict prostate cancer-specific mortality (PCSM) and to validate that they could predict aggressive biochemical recurrence (BCR). Prostate-specific antigen (PSA), grade, and stage are the classic triad used to predict BCR after radical prostatectomy (RP...
[ "Risk stratification in medullary thyroid cancer (MTC) has traditionally relied on standardized anatomic staging systems that, despite providing valuable prognostic information, do not adequately predict the risk of persistent or recurrent disease. As dynamic risk stratification has been demonstrated to be clinical...
pubmedqa
{ "query": "Represent the Biomedical question for retrieving relevant paragraphs:", "pos": "Represent the Biomedical paragraph for retrieval:", "neg": "Represent the Biomedical paragraph for retrieval:" }
Are reports of mechanical dysfunction in chronic oro-facial pain related to somatisation?
[ "(i) To examine the association between self-reported mechanical factors and chronic oro-facial pain. (ii) To test the hypothesis that this relationship could be explained by: (a) reporting of psychological factors, (b) common association of self-reported mechanical factors with other unexplained syndromes. A popul...
[ "No previous studies have investigated the psychiatric characteristics of patients with postherpetic neuralgia (PHN). Similarly, no studies have been performed on patients with different chronic somatic symptoms due to a defined medical disease to compare the characteristics of psychiatric morbidity associated with...
pubmedqa
{ "query": "Represent the Biomedical query for retrieving relevant paragraphs:", "pos": "Represent the Biomedical paragraph for retrieval:", "neg": "Represent the Biomedical paragraph for retrieval:" }
Amblyopia: is visual loss permanent?
[ "The records of 465 patients with an established diagnosis of age related macular degeneration who had attended a specialist macular clinic between 1990 and 1998 were scrutinised. A full clinical examination and standardised refraction had been carried out in 189 of these cases on a minimum of two occasions. Cases ...
[ "To present two cases of pediatric Cogan Syndrome and to highlight the differences between the adult and pediatric forms of the disease, as well as the importance of early diagnosis and treatment. Interventional case report. Institutional setting. Corneal lesions were much more diffuse than those observed in adult ...
pubmedqa
{ "query": "Represent the Biomedical query for retrieving relevant passages:", "pos": "Represent the Biomedical passage for retrieval:", "neg": "Represent the Biomedical passage for retrieval:" }
Implementation of epidural analgesia for labor: is the standard of effective analgesia reachable in all women?
[ "Social and cultural factors combined with little information may prevent the diffusion of epidural analgesia for pain relief during childbirth. The present study was launched contemporarily to the implementation of analgesia for labor in our Department in order to perform a 2 years audit on its use. The goal is to...
[ "Transversus abdominis plane blocks have been recently utilized for analgesia after cesarean delivery. However, little data concerning continuous transversus abdominis plane blocks has been reported in the existing literature. Available studies mainly examine the efficacy of single-injection blocks, and only one sm...
pubmedqa
{ "query": "Represent the Biomedical query for retrieving relevant documents:", "pos": "Represent the Biomedical document for retrieval:", "neg": "Represent the Biomedical document for retrieval:" }
Does HER2 immunoreactivity provide prognostic information in locally advanced urothelial carcinoma patients receiving adjuvant M-VEC chemotherapy?
[ "To evaluate the impact of HER2 immunoreactivity on clinical outcome in locally advanced urothelial carcinoma patients who received surgery alone, or methotrexate, vinblastine, epirubicin, and cisplatin (M-VEC) as adjuvant chemotherapy. We studied 114 formalin-fixed paraffin-embedded specimens obtained from locally...
[ "This article reviews the recent seminal studies in esophagogastric cancer. Regular low aspirin use may reduce the risk of esophagogastric cancer. Laparoscopic resection of locally advanced gastric cancer appears equivalent to open resection. There is no survival benefit for the addition of postoperative radiation ...
pubmedqa
{ "query": "Represent the Biomedical query for retrieving relevant paragraphs:", "pos": "Represent the Biomedical paragraph for retrieval:", "neg": "Represent the Biomedical paragraph for retrieval:" }
Is halofantrine ototoxic?
[ "Halofantrine is a newly developed antimalarial drug used for the treatment of Plasmodium falciparum malaria. The introduction of this drug has been delayed because of its possible side effects, and due to insufficient studies on adverse reactions in humans. There have been no studies investigating its effect on he...
[ "What is the effect of estrogen on heparanase procogulant activity?" ]
pubmedqa
{ "query": "Represent the Biomedical question for retrieving relevant passages:", "pos": "Represent the Biomedical passage for retrieval:", "neg": "Represent the Biomedical passage for retrieval:" }
Visceral adipose tissue area measurement at a single level: can it represent visceral adipose tissue volume?
[ "Measurement of visceral adipose tissue (VAT) needs to be accurate and sensitive to change for risk monitoring. The purpose of this study is to determine the CT slice location where VAT area can best reflect changes in VAT volume and body weight. 60 plain abdominal CT images from 30 males [mean age (range) 51 (41-6...
[ "A number of anatomic sites are used for the measurement of waist circumference. A number of studies have documented differences in the absolute values of waist circumference measurements across these common sites in adults. It is unclear whether waist circumference measurement site alters the relationship with abd...
pubmedqa
{ "query": "Represent the Biomedical question for retrieving relevant documents:", "pos": "Represent the Biomedical document for retrieval:", "neg": "Represent the Biomedical document for retrieval:" }
Necrotizing fasciitis: an indication for hyperbaric oxygenation therapy?
[ "The accepted treatment protocol for necrotizing fasciitis (NF) consists of extensive surgery and wide spectrum antibiotics. Hyperbaric oxygenation (HBO) has been recommended as adjuvant therapy for NF, improving patient mortality and outcome. However, the beneficial effect of HBO for NF remains controversial. A re...
[ "Is there a non-invasive biomarker for the diagnosis of testicular inflammatory lesions?" ]
pubmedqa
{ "query": "Represent the Biomedical question for retrieving relevant paragraphs:", "pos": "Represent the Biomedical paragraph for retrieval:", "neg": "Represent the Biomedical paragraph for retrieval:" }
Is the Hawkins sign able to predict necrosis in fractures of the neck of the astragalus?
[ "To assess if the Hawkins sign can predict whether or not astragalus fractures of the neck will develop avascular necrosis. It is also assessed whether the occurrence of this complication is related to the displacement of the fracture, soft tissue injury, or delay in the reduction or surgery. The results were compa...
[ "It is known that posterior malleolar fracture is often associated with tibial diaphyseal fractures. However, in literature there are very few studies on tibial shaft fractures with respect to posterior malleolus fragment. We hypothesized that the incidence of posterior malleolar fracture is higher than in previous...
pubmedqa
{ "query": "Represent the Biomedical query for retrieving relevant documents:", "pos": "Represent the Biomedical document for retrieval:", "neg": "Represent the Biomedical document for retrieval:" }
Is a mandatory general surgery rotation necessary in the surgical clerkship?
[ "Changes in the spectrum of general surgery and the delivery of surgical care have placed the requirement for a mandatory general surgery rotation in the surgical clerkship in question. We tested the hypothesis that equal mastery of surgical clerkship objectives can be obtained in a clerkship with and without gener...
[ "To provide an updated report on the status of urology education in the United States. Forty-one randomly selected accredited medical schools in the United States were surveyed concerning their urology curriculum. All schools were included in the randomization, even those that had not produced any successful urolog...
pubmedqa
{ "query": "Represent the Biomedical question for retrieving relevant passages:", "pos": "Represent the Biomedical passage for retrieval:", "neg": "Represent the Biomedical passage for retrieval:" }
Is Acupuncture Efficacious for Treating Phonotraumatic Vocal Pathologies?
[ "To investigate the effectiveness of acupuncture in treating phonotraumatic vocal fold lesions.STUDY DESIGN/ A total of 123 dysphonic individuals with benign vocal pathologies were recruited. They were given either genuine acupuncture (n = 40), sham acupuncture (n = 44), or no treatment (n = 39) for 6 weeks (two 30...
[ "Is there a non-invasive biomarker for the diagnosis of testicular inflammatory lesions?" ]
pubmedqa
{ "query": "Represent the Biomedical query for retrieving relevant paragraphs:", "pos": "Represent the Biomedical paragraph for retrieval:", "neg": "Represent the Biomedical paragraph for retrieval:" }
Is aneurysm repair justified for the patients aged 80 or older after aneurysmal subarachnoid hemorrhage?
[ "With the advancement of an aging society in the world, an increasing number of elderly patients have been hospitalized due to aneurysmal subarachnoid hemorrhage (aSAH). There is no study that compares the elderly cases of aSAH who receive the definitive treatment with those who treated conservatively. The aim of t...
[ "Infective endocarditis is often associated with cerebral complications, the most serious of which is intraoperative hemorrhagic stroke owing to anticoagulation for cardiopulmonary bypass. However, its prevalence and risk factors are unknown. We evaluated the prevalence and risk factors of intraoperative hemorrhagi...
pubmedqa
{ "query": "Represent the Biomedical question for retrieving relevant passages:", "pos": "Represent the Biomedical passage for retrieval:", "neg": "Represent the Biomedical passage for retrieval:" }
Do general practice characteristics influence uptake of an information technology (IT) innovation in primary care?
[ "Recent evaluations of IT innovations in primary care have highlighted variations between centres and practices in uptake and use. We evaluated whether structural characteristics of a general practice were associated with variations in use of a web-based clinical information system underpinning a Managed Clinical N...
[ "Quality improvements achieved by applying the systems approach to assess the clinical effectiveness, operational efficiency, and financial feasibility of a pharmacist-managed vancomycin dosing service are described." ]
pubmedqa
{ "query": "Represent the Biomedical query for retrieving relevant passages:", "pos": "Represent the Biomedical passage for retrieval:", "neg": "Represent the Biomedical passage for retrieval:" }
Prognosis of well differentiated small hepatocellular carcinoma--is well differentiated hepatocellular carcinoma clinically early cancer?
[ "The purpose of this study is to examine whether or not well differentiated (w-d) hepatocellular carcinoma (HCC) is indeed clinically early cancer. Seventy six patients with solitary small HCCs up to 3 cm in diameter, who underwent hepatectomy, were observed for at least 2 years for possible recurrence. These patie...
[ "Identification of the risk factors of multicentric hepatocarcinogenesis is important for the clinical management of hepatocellular carcinoma. We investigated hyperplastic foci in non-cancerous liver parenchyma, and clarified their pathological features and clinical significance. Hyperplastic foci were defined as h...
pubmedqa
{ "query": "Represent the Biomedical question for retrieving relevant paragraphs:", "pos": "Represent the Biomedical paragraph for retrieval:", "neg": "Represent the Biomedical paragraph for retrieval:" }
Do follow-up recommendations for abnormal Papanicolaou smears influence patient adherence?
[ "To compare adherence to follow-up recommendations for colposcopy or repeated Papanicolaou (Pap) smears for women with previously abnormal Pap smear results. Retrospective cohort study. Three northern California family planning clinics. All women with abnormal Pap smear results referred for initial colposcopy and a...
[ "Is optimal adherence to guideline recommendations in intrauterine insemination (IUI) care cost-effective from a societal perspective when compared with suboptimal adherence to guideline recommendations?" ]
pubmedqa
{ "query": "Represent the Biomedical query for retrieving relevant documents:", "pos": "Represent the Biomedical document for retrieval:", "neg": "Represent the Biomedical document for retrieval:" }
Biomolecular identification of allergenic pollen: a new perspective for aerobiological monitoring?
[ "Accurate and updated information on airborne pollen in specific areas can help allergic patients. Current monitoring systems are based on a morphologic identification approach, a time-consuming method that may represent a limiting factor for sampling network enhancement. To verify the feasibility of developing a r...
[ "To review the role of immunoglobulin E (IgE)-mediated inflammation in the pathogenesis of asthma, limitations of standard therapies, and IgE as a logical target for therapy with omalizumab aimed at attaining asthma symptom control. Review of worldwide scientific literature on the role of IgE-mediated inflammation ...
pubmedqa
{ "query": "Represent the Biomedical question for retrieving relevant passages:", "pos": "Represent the Biomedical passage for retrieval:", "neg": "Represent the Biomedical passage for retrieval:" }
Does diabetes mellitus influence the efficacy of FDG-PET in the diagnosis of cervical cancer?
[ "Compared with computed tomography (CT) and magnetic resonance imaging (MRI), positron emission tomography (PET) may have additional value in the assessment of primary and recurrent cervical cancer. However, the degree of tumour uptake of (18)F-2-fluoro-2-deoxy-D: -glucose (FDG) uptake is sometimes influenced by di...
[ "Is there a non-invasive biomarker for the diagnosis of testicular inflammatory lesions?" ]
pubmedqa
{ "query": "Represent the Biomedical query for retrieving relevant paragraphs:", "pos": "Represent the Biomedical paragraph for retrieval:", "neg": "Represent the Biomedical paragraph for retrieval:" }
Biomechanical and wound healing characteristics of corneas after excimer laser keratorefractive surgery: is there a difference between advanced surface ablation and sub-Bowman's keratomileusis?
[ "To describe the biomechanical and wound healing characteristics of corneas after excimer laser keratorefractive surgery. Histologic, ultrastructural, and cohesive tensile strength evaluations were performed on 25 normal human corneal specimens, 206 uncomplicated LASIK specimens, 17 uncomplicated sub-Bowman's kerat...
[ "To evaluate the effect of mitomycin C (MMC) on the exacerbation of corneal opacity that occurs in patients with granular corneal dystrophy type II (GCD II) after refractive corneal surface ablation. Ten eyes of patients with GCD II who underwent refractive corneal surface ablation with MMC were compared with 10 ey...
pubmedqa
{ "query": "Represent the Biomedical query for retrieving relevant passages:", "pos": "Represent the Biomedical passage for retrieval:", "neg": "Represent the Biomedical passage for retrieval:" }
Does radiotherapy of the primary rectal cancer affect prognosis after pelvic exenteration for recurrent rectal cancer?
[ "Radiotherapy reduces local recurrence rates but is also capable of short- and long-term toxicity. It may also render treatment of local recurrence more challenging if it develops despite previous radiotherapy. This study examined the impact of radiotherapy for the primary rectal cancer on outcomes after pelvic exe...
[ "The timing of surgery and postoperative radiotherapy--especially if combined with chemotherapy--has been a subject of interest over the past years. This analysis was based on a literature review of mostly retrospective publications. Data concerning the interval between surgery and radiotherapy were correlated with...
pubmedqa
{ "query": "Represent the Biomedical query for retrieving relevant passages:", "pos": "Represent the Biomedical passage for retrieval:", "neg": "Represent the Biomedical passage for retrieval:" }
Can a practicing surgeon detect early lymphedema reliably?
[ "Lymphedema may be identified by simpler circumference changes as compared with changes in limb volume. Ninety breast cancer patients were prospectively enrolled in an academic trial, and seven upper extremity circumferences were measured quarterly for 3 years. A 10% volume increase or greater than 1 cm increase in...
[ "Is there a non-invasive biomarker for the diagnosis of testicular inflammatory lesions?" ]
pubmedqa
{ "query": "Represent the Biomedical question for retrieving relevant paragraphs:", "pos": "Represent the Biomedical paragraph for retrieval:", "neg": "Represent the Biomedical paragraph for retrieval:" }
Colorectal cancer with synchronous liver metastases: does global management at the same centre improve results?
[ "Synchronous liver metastases (SLM) occur in 20% of colorectal cancers (CRC). Resection of SLM and CLC can be undertaken at different centres (separate management, SM) or at the same centre (global management, GM). Retrospective study of SLM and CRC resections carried out during 01/2000 - 12/2006 by SM or GM, using...
[ "US and European practices differ with respect to treating hepatoblastoma (HB). Should chemotherapy be given prior to resection in all cases, and even without biopsy confirmation (SIOPEL)? US data indicate that 40% of HBs are primarily resectable with no operative mortality and that those with pure fetal histology ...
pubmedqa
{ "query": "Represent the Biomedical query for retrieving relevant documents:", "pos": "Represent the Biomedical document for retrieval:", "neg": "Represent the Biomedical document for retrieval:" }
Is motion perception deficit in schizophrenia a consequence of eye-tracking abnormality?
[ "Studies have shown that schizophrenia patients have motion perception deficit, which was thought to cause eye-tracking abnormality in schizophrenia. However, eye movement closely interacts with motion perception. The known eye-tracking difficulties in schizophrenia patients may interact with their motion perceptio...
[ "To evaluate cognitive control in children with attention-deficit/hyperactivity disorder (ADHD) using oculomotor tests of executive function. Cross-sectional study of children aged 8 to 13 years with ADHD (n = 26) and controls (n = 33) used oculomotor tasks to assess sensorimotor function (visually guided saccades)...
pubmedqa
{ "query": "Represent the Biomedical question for retrieving relevant documents:", "pos": "Represent the Biomedical document for retrieval:", "neg": "Represent the Biomedical document for retrieval:" }
Transgastric endoscopic splenectomy: is it possible?
[ "We have previously reported the feasibility of diagnostic and therapeutic peritoneoscopy including liver biopsy, gastrojejunostomy, and tubal ligation by an oral transgastric approach. We present results of per-oral transgastric splenectomy in a porcine model. The goal of this study was to determine the technical ...
[ "Management of postoperative esophagojejunal anastomotic leakage after total gastrectomy represents a very challenging event. Surgical repair is difficult, and conservative treatment can predispose to more severe complications. Endoclips and self-expanding stents are useful endoscopic therapeutic options but presen...
pubmedqa
{ "query": "Represent the Biomedical query for retrieving relevant passages:", "pos": "Represent the Biomedical passage for retrieval:", "neg": "Represent the Biomedical passage for retrieval:" }
It's Fournier's gangrene still dangerous?
[ "Fournier's gangrene is known to have an impact in the morbidity and despite antibiotics and aggressive debridement, the mortality rate remains high. To assess the morbidity and mortality in the treatment of Fournier's gangrene in our experience. The medical records of 14 patients with Fournier's gangrene who prese...
[ "To present the evidence that alcoholism is a disease." ]
pubmedqa
{ "query": "Represent the Biomedical query for retrieving relevant passages:", "pos": "Represent the Biomedical passage for retrieval:", "neg": "Represent the Biomedical passage for retrieval:" }
Is it appropriate to implant kidneys from elderly donors in young recipients?
[ "Kidneys from elderly donors tend to be implanted in recipients who are also elderly. We present the results obtained after 10 years of evolution on transplanting elderly kidneys into young recipients. Ninety-one consecutive transplants are studied, carried out in our center with kidneys from cadaver donors older t...
[ "Concern that morbidly obese (body mass index [BMI] 35) kidney transplant recipients have worse outcomes than non-morbidly obese recipients leads many transplant centers to deny them the benefit of kidney transplantation. These concerns are supported by guidelines recently published by the American Society of Trans...
pubmedqa
{ "query": "Represent the Biomedical question for retrieving relevant passages:", "pos": "Represent the Biomedical passage for retrieval:", "neg": "Represent the Biomedical passage for retrieval:" }
Do provider service networks result in lower expenditures compared with HMOs or primary care case management in Florida's Medicaid program?
[ "To determine the impact of Florida's Medicaid Demonstration 4 years post-implementation on per member per month (PMPM) Medicaid expenditures and whether receiving care through HMOs versus provider service networks (PSNs) in the Demonstration was associated with PMPM expenditures.DATA: Florida Medicaid claims from ...
[ "Health plans commonly face the conflicting demands of trying to provide access to novel technologies, including new classes of medications, while trying to contain costs. These demands are particularly acute for California's Medicaid program, known as Medi-Cal, which is responsible for delivery of medical care to ...
pubmedqa
{ "query": "Represent the Biomedical question for retrieving relevant paragraphs:", "pos": "Represent the Biomedical paragraph for retrieval:", "neg": "Represent the Biomedical paragraph for retrieval:" }
Assessment of carotid artery stenosis before coronary artery bypass surgery. Is it always necessary?
[ "Extracranial internal carotid artery stenosis is a risk factor for perioperative stroke in patients undergoing coronary artery bypass surgery (CAB). Although selective and non-selective methods of preoperative carotid screening have been advocated, it remains unclear if this screening is clinically relevant.AIM: T...
[ "Statins are an essential component of the therapeutic approach of patients with atherosclerotic disease. Statin use is also associated with improved peri-operative and long-term outcomes in these patients. We aimed to define the role of statin treatment in patients undergoing percutaneous revascularization procedu...
pubmedqa
{ "query": "Represent the Biomedical question for retrieving relevant paragraphs:", "pos": "Represent the Biomedical paragraph for retrieval:", "neg": "Represent the Biomedical paragraph for retrieval:" }
Should direct mesocolon invasion be included in T4 for the staging of gastric cancer?
[ "One of the sites most frequently invaded by gastric cancer is the mesocolon; however, the UICC does not mention this anatomical site as an adjacent structure involved in gastric cancer. The purpose of this study was to characterize and classify mesocolon invasion from gastric cancer. We examined 806 patients who u...
[ "The clinical and prognostic value of the previous node classification of TNM staging in early gastric cancer (EGC) has been less definitive. The aim was to assess the suitability of the revised node staging for prediction of clinical behavior of EGC. Between 2005 and 2008, 1,845 patients were diagnosed with EGC an...
pubmedqa
{ "query": "Represent the Biomedical query for retrieving relevant paragraphs:", "pos": "Represent the Biomedical paragraph for retrieval:", "neg": "Represent the Biomedical paragraph for retrieval:" }
Do Surrogates of Injury Severity Influence the Occurrence of Heterotopic Ossification in Fractures of the Acetabulum?
[ "To determine the relationship between injury severity surrogates and other patient factors with the development and severity of heterotopic ossification (HO) following open reduction internal fixation of acetabular fractures treated with a posterior approach. Retrospective review. Academic level 1 trauma center. T...
[ "Is there a non-invasive biomarker for the diagnosis of testicular inflammatory lesions?" ]
pubmedqa
{ "query": "Represent the Biomedical query for retrieving relevant documents:", "pos": "Represent the Biomedical document for retrieval:", "neg": "Represent the Biomedical document for retrieval:" }
Does pretreatment with statins improve clinical outcome after stroke?
[ "In primary and secondary prevention trials, statins have been shown to reduce the risk of stroke. In addition to lipid lowering, statins have a number of antiatherothrombotic and neuroprotective properties. In a preliminary observational study, we explored whether clinical outcome is improved in patients who are o...
[ "Myocardial damage that is associated with percutaneous coronary intervention (PCI) partially affects the results of the procedure, and is related to medium-term cardiovascular death. Remote postischemic conditioning might reduce the myocardial lesions that are associated with PCI, but perhaps less so in diabetics....
pubmedqa
{ "query": "Represent the Biomedical query for retrieving relevant paragraphs:", "pos": "Represent the Biomedical paragraph for retrieval:", "neg": "Represent the Biomedical paragraph for retrieval:" }
Processing fluency effects: can the content and presentation of participant information sheets influence recruitment and participation for an antenatal intervention?
[ "To assess the extent to which the title and font of participant information sheets (PISs) can influence pregnant women's and trainee midwives' perceptions of an antenatal intervention. Pregnant women (n=35) and trainee midwives (n=36) were randomly presented with one of four PISs where the title and font of the PI...
[ "Previous research (Webb, Simmons, & Brandon, 2005) suggested that smokers' reactions to self-help materials were more positive if they believed that the materials had been personally tailored to their individual characteristics and if they held expectancies that tailored interventions are superior to standard, or ...
pubmedqa
{ "query": "Represent the Biomedical question for retrieving relevant passages:", "pos": "Represent the Biomedical passage for retrieval:", "neg": "Represent the Biomedical passage for retrieval:" }
Sternal fracture in growing children : A rare and often overlooked fracture?
[ "Sternal fractures in childhood are rare. The aim of the study was to investigate the accident mechanism, the detection of radiological and sonographical criteria and consideration of associated injuries. In the period from January 2010 to December 2012 all inpatients and outpatients with sternal fractures were rec...
[ "Tumors and tumorlike lesions of the tubular bones of the hand, often incidentally discovered lesions, present a unique but challenging differential diagnosis." ]
pubmedqa
{ "query": "Represent the Biomedical question for retrieving relevant passages:", "pos": "Represent the Biomedical passage for retrieval:", "neg": "Represent the Biomedical passage for retrieval:" }
Is there a correlation between androgens and sexual desire in women?
[ "For women, the correlation between circulating androgens and sexual desire is inconclusive. Substitution with androgens at physiological levels improves sexual function in women who experience decreased sexual desire and androgen deficiency from surgical menopause, pituitary disease, and age-related decline in and...
[ "What are the lifestyle choices and dietary aspects of women about to undergo fertility treatment in New Zealand?" ]
pubmedqa
{ "query": "Represent the Biomedical question for retrieving relevant documents:", "pos": "Represent the Biomedical document for retrieval:", "neg": "Represent the Biomedical document for retrieval:" }
Does immediate breast reconstruction compromise the delivery of adjuvant chemotherapy?
[ "Immediate breast reconstruction (IBR) provides psychological benefit to many early breast cancer patients however concerns persist regarding its potential impact on chemotherapy delivery. We investigated the association between IBR, complications and adjuvant chemotherapy delivery. Retrospective analysis of patien...
[ "This article reviews the recent seminal studies in esophagogastric cancer. Regular low aspirin use may reduce the risk of esophagogastric cancer. Laparoscopic resection of locally advanced gastric cancer appears equivalent to open resection. There is no survival benefit for the addition of postoperative radiation ...
pubmedqa
{ "query": "Represent the Biomedical question for retrieving relevant documents:", "pos": "Represent the Biomedical document for retrieval:", "neg": "Represent the Biomedical document for retrieval:" }
Human papillomavirus and pterygium. Is the virus a risk factor?
[ "Pterygium is a disease of unknown origin and pathogenesis that might be vision threatening. It is characterised by a wing-like conjunctival overgrowth of the cornea. Several studies have investigated human papillomavirus (HPV) as a risk factor for the development of pterygia, but the results are inconclusive.AIM: ...
[ "The growth of primary low-grade B-cell gastric mucosa-associated lymphoid tissue (MALT) lymphoma is an antigen-dependent process We were able to document the influence of Helicobacter pylori on the natural history of primary low-grade B-cell gastric MALT lymphoma in a case investigated by means of polymerase chain...
pubmedqa
{ "query": "Represent the Biomedical query for retrieving relevant passages:", "pos": "Represent the Biomedical passage for retrieval:", "neg": "Represent the Biomedical passage for retrieval:" }
Can PRISM predict length of PICU stay?
[ "PRISM is claimed to score disease severity which has attributed an impact on length of PICU stay (LOS). To determine the impact of PRISM on LOS, and evaluate an Artificial Neural Network's (ANN) performance to estimate LOS from PRISM item patterns. Retrospectively we performed correlation and regression analyses o...
[ "Readmission to ICU following discharge is associated with increased length of stay (LOS), increased rates of mortality, morbidity and resource consumption. Reducing readmission rates is one of the key aims of the Intensive Care Unit liaison nurse (ICULN). Our objective was to identify factors associated with readm...
pubmedqa
{ "query": "Represent the Biomedical question for retrieving relevant documents:", "pos": "Represent the Biomedical document for retrieval:", "neg": "Represent the Biomedical document for retrieval:" }
Can predilatation in transcatheter aortic valve implantation be omitted?
[ "The use of a balloon expandable stent valve includes balloon predilatation of the aortic stenosis before valve deployment. The aim of the study was to see whether or not balloon predilatation is necessary in transcatheter aortic valve replacement (TAVI). Sixty consecutive TAVI patients were randomized to the stand...
[ "Statins are an essential component of the therapeutic approach of patients with atherosclerotic disease. Statin use is also associated with improved peri-operative and long-term outcomes in these patients. We aimed to define the role of statin treatment in patients undergoing percutaneous revascularization procedu...
pubmedqa
{ "query": "Represent the Biomedical query for retrieving relevant paragraphs:", "pos": "Represent the Biomedical paragraph for retrieval:", "neg": "Represent the Biomedical paragraph for retrieval:" }
Autoerotic asphyxiation: secret pleasure--lethal outcome?
[ "Voluntary asphyxiation among children, preteens, and adolescents by hanging or other means of inducing hypoxia/anoxia to enhance sexual excitement is not uncommon and can lead to unintended death. This study addresses autoerotic asphyxiation (AEA) with the intent of increasing pediatricians' knowledge of the syndr...
[ "What are the lifestyle choices and dietary aspects of women about to undergo fertility treatment in New Zealand?" ]
pubmedqa
{ "query": "Represent the Biomedical query for retrieving relevant passages:", "pos": "Represent the Biomedical passage for retrieval:", "neg": "Represent the Biomedical passage for retrieval:" }
Major depression and alcohol use disorder in adolescence: Does comorbidity lead to poorer outcomes of depression?
[ "Comorbid major depression (MD) and alcohol use disorder (AUD), particularly in adolescents, have been shown to be associated with poorer subsequent MD outcomes. Longitudinal data were used to model associations between a four-level classification of MD/AUD during the period 15-18 years (neither; MD-only; AUD-only;...
[ "Adolescent cannabis use has been shown in many studies to increase the risk of later psychosis. Childhood trauma is associated with both substance misuse and risk for psychosis. In this study our aim was to investigate whether there is a significant interaction between cannabis use and childhood trauma in increasi...
pubmedqa
{ "query": "Represent the Biomedical query for retrieving relevant passages:", "pos": "Represent the Biomedical passage for retrieval:", "neg": "Represent the Biomedical passage for retrieval:" }
Cold preparation use in young children after FDA warnings: do concerns still exist?
[ "To characterize the use and delivery of cough and cold medicines in children younger than 6 presenting to an inner-city pediatric emergency department (PED) following 2007 FDA warnings. A cross-sectional observational study was performed using a convenience sampling of PED patients during the fall of 2010. Caregiv...
[ "What are the lifestyle choices and dietary aspects of women about to undergo fertility treatment in New Zealand?" ]
pubmedqa
{ "query": "Represent the Biomedical query for retrieving relevant paragraphs:", "pos": "Represent the Biomedical paragraph for retrieval:", "neg": "Represent the Biomedical paragraph for retrieval:" }
Does a 4 diagram manual enable laypersons to operate the Laryngeal Mask Supreme®?
[ "Bystander resuscitation plays an important role in lifesaving cardiopulmonary resuscitation (CPR). A significant reduction in the \"no-flow-time\", quantitatively better chest compressions and an improved quality of ventilation can be demonstrated during CPR using supraglottic airway devices (SADs). Previous studi...
[ "Does age of G-1 PLUS v5 embryo culture medium affect IVF outcome?" ]
pubmedqa
{ "query": "Represent the Biomedical question for retrieving relevant passages:", "pos": "Represent the Biomedical passage for retrieval:", "neg": "Represent the Biomedical passage for retrieval:" }
Can we measure mesopic pupil size with the cobalt blue light slit-lamp biomicroscopy method?
[ "The aim of this work is to assess a previously described slit-lamp biomicroscopy-based method (SLBM) for measuring pupil diameter and compare it to Colvard infrared pupillometry (CIP). Two examiners performed three repeated measurements with each instrument in 40 healthy eyes. We determined the agreement of SLBM a...
[ "To investigate the factors that govern the manifestation of hyperopic refractive errors of pre-school children when tested with and without the application of cycloplegics. Forty-three pre-school children (mean age, 3.68 +/- 0.59 years) were tested before and during cycloplegia in the following order: retinoscopy ...
pubmedqa
{ "query": "Represent the Biomedical question for retrieving relevant documents:", "pos": "Represent the Biomedical document for retrieval:", "neg": "Represent the Biomedical document for retrieval:" }
Should circumcision be performed in childhood?
[ "To evaluate prepuce development and retractibility in a group of boys. To point out the value of circumcision and prepucial forced dilation during childhood. Prepuce development and retractibility were evaluated in 400 boys ages between 0-16 year old. In boys under 1 year prepuce retractibility (assessed only in c...
[ "To compare fear of circumcision, before, immediately after, and ten days after the operation. This was a case-control study in which participants in the operation group consisted of children admitted for circumcision at the outpatient clinics of a hospital. The Children's Fear Scale and the Venham Picture Test wer...
pubmedqa
{ "query": "Represent the Biomedical query for retrieving relevant paragraphs:", "pos": "Represent the Biomedical paragraph for retrieval:", "neg": "Represent the Biomedical paragraph for retrieval:" }
Does a colonoscopy after acute diverticulitis affect its management?
[ "Medical records of 220 patients hospitalized for acute diverticulitis between June 1, 2002 and September 1, 2009 were reviewed. Acute diverticulitis was diagnosed by clinical criteria and characteristic CT findings. Fifteen patients were excluded either because of questionable CT or hematochezia. Mean age was 61.8...
[ "The optimal diet for uncomplicated diverticulitis is unclear. Guidelines refrain from recommendation due to lack of objective information. The aim of the study was to determine whether an unrestricted diet during a first acute episode of uncomplicated diverticulitis is safe. A prospective cohort study was performe...
pubmedqa
{ "query": "Represent the Biomedical query for retrieving relevant passages:", "pos": "Represent the Biomedical passage for retrieval:", "neg": "Represent the Biomedical passage for retrieval:" }
Do instrumental activities of daily living predict dementia at 1- and 2-year follow-up?
[ "To investigate whether problems in instrumental activities of daily living (IADL) can add to conventionally used clinical measurements in helping to predict a diagnosis of dementia at 1- and 2-year follow-up. Multicenter prospective cohort study. Memory clinics in Europe. Individuals aged 55 and older without deme...
[ "Systemic low-grade inflammation has repeatedly been associated with depression in old age, but the relationship with apathy is less clear. The present study assessed whether C-reactive protein (CRP) is differentially associated with symptoms of apathy and depression. A population-based cohort study was carried-out...
pubmedqa
{ "query": "Represent the Biomedical query for retrieving relevant documents:", "pos": "Represent the Biomedical document for retrieval:", "neg": "Represent the Biomedical document for retrieval:" }
Does the Simultaneous Use of a Neuroendoscope Influence the Incidence of Ventriculoperitoneal Shunt Infection?
[ "The relationship between the use of an endoscope during ventriculoperitoneal shunt (VPS) procedures and infection remains poorly defined. In this study, we sought to analyze whether the simultaneous use of an endoscope could in fact increase the infection rate associated with VPS procedures. This study included 43...
[ "Is there a non-invasive biomarker for the diagnosis of testicular inflammatory lesions?" ]
pubmedqa
{ "query": "Represent the Biomedical query for retrieving relevant passages:", "pos": "Represent the Biomedical passage for retrieval:", "neg": "Represent the Biomedical passage for retrieval:" }
Body perception: do parents, their children, and their children's physicians perceive body image differently?
[ "To compare children's, parents' and physicians' perceptions of children's body size. We administered a structured questionnaire of body size perception using a descriptive Likert scale keyed to body image figures to children ages 12 to 18 years. The same scale was given to parents of children ages 5 to 18 years. T...
[ "To determine whether self-esteem among children with cystic fibrosis (CF) and their healthy siblings differs from that of a healthy reference group and whether there are differences within and between sibling pairs. All Swedish CF children 6-14 y old with a healthy sibling in the same age range (n=65) were invited...
pubmedqa
{ "query": "Represent the Biomedical question for retrieving relevant documents:", "pos": "Represent the Biomedical document for retrieval:", "neg": "Represent the Biomedical document for retrieval:" }
Is a specialised training of phonological awareness indicated in every preschool child?
[ "In a prospective study 218 preschool children were enrolled (stratified in 2 training programs, one specialized for phonologic awareness in order to prevent dyslexia, the other consisting in training of general perception) during the last year of kindergarten. After finishing the first grade 131 children were comp...
[ "Results of language therapy with adolescents and children with autistic spectrum disorders. to identify changes, after a six-month period of speech-language therapy, in a group of adolescents and to compare them with a group of children. Data referring to the communicative profile and social-cognitive performance ...
pubmedqa
{ "query": "Represent the Biomedical query for retrieving relevant passages:", "pos": "Represent the Biomedical passage for retrieval:", "neg": "Represent the Biomedical passage for retrieval:" }
Is there any relationship between streptococcal infection and multiple sclerosis?
[ "Multiple sclerosis (MS) is an immune-mediated inflammatory demyelinating disease of uncertain etiology. Although the mechanisms of inducting autoimmunity by some of the infectious agents have been investigated, there is not yet enough research on streptococcal infections.MATERIAL/ To understand the effect of past ...
[ "Is there a non-invasive biomarker for the diagnosis of testicular inflammatory lesions?" ]
pubmedqa
{ "query": "Represent the Biomedical query for retrieving relevant paragraphs:", "pos": "Represent the Biomedical paragraph for retrieval:", "neg": "Represent the Biomedical paragraph for retrieval:" }
Is the combination with 2-methoxyestradiol able to reduce the dosages of chemotherapeutices in the treatment of human ovarian cancer?
[ "The endogenous estradiol metabolite, 2-methoxyestradiol (2ME), has been shown to be a potent inhibitor of cell growth and a strong anti-angiogenic substance. We investigated for the first time whether in vitro combinations of 2ME with various chemotherapeutic compounds may result in an additive inhibitory effect o...
[ "Chemicals that interfere with reactive oxygen species metabolism can act as potential candidates for the treatment of cancer. Some of the glucosides of citrus limonin inhibit the endogenously generated reactive oxygen species. The aim is to study the interactions of limonin with chemotherapy. Breast cancer cell li...
pubmedqa
{ "query": "Represent the Biomedical question for retrieving relevant passages:", "pos": "Represent the Biomedical passage for retrieval:", "neg": "Represent the Biomedical passage for retrieval:" }
Assessing joint line positions by means of the contralateral knee: a new approach for planning knee revision surgery?
[ "Reconstructing the natural joint line in knee revision surgery improves clinical and functional outcome but may be challenging when both cartilage and bone were removed during previous operations. Assessing joint lines (JLs) by means of bony landmarks is inadvisable because of large variations in human anatomy. Be...
[ "An important factor in the functional results after total knee arthroplasty is the achieved maximal flexion. The main purpose of this study was to compare the maximal knee flexion one year after surgery in patients who received either the bicruciate substituting knee system or the conventional posterior stabilized...
pubmedqa
{ "query": "Represent the Biomedical query for retrieving relevant passages:", "pos": "Represent the Biomedical passage for retrieval:", "neg": "Represent the Biomedical passage for retrieval:" }
Does the type of tibial component affect mechanical alignment in unicompartmental knee replacement?
[ "There are a number of factors responsible for the longevity of unicompartmental knee replacements (UKR). These include the magnitude of postoperative alignment and the type of material used. The effect of component design and material on postoperative alignment, however, has not been explored. We retrospectively r...
[ "All-polyethylene tibias (APT) are under-utilized in most of the Western countries, due to a shift from the original all-polyethylene design to metal-backed tibia (MBT) components. Only few total knee prostheses allow direct comparison between APT and MBT components, due to different geometric designs in many syste...
pubmedqa
{ "query": "Represent the Biomedical query for retrieving relevant documents:", "pos": "Represent the Biomedical document for retrieval:", "neg": "Represent the Biomedical document for retrieval:" }
Is tumour expression of VEGF associated with venous invasion and survival in pT3 renal cell carcinoma?
[ "To determine whether there is a relationship between VEGF expression and renal vein and vena cava invasion in stage pT3 renal cell carcinoma and to evaluate the impact of VEGF expression on survival in pT3 renal cell carcinoma. 78 patients with a pT3a or pT3b tumour without vena cava invasion or pT3b tumour with v...
[ "EpCAM is an adhesion molecule of the basolateral membranes in a variety of epithelial cells. Over-expression has been detected in many epithelial tumours and has been associated with high stage, high grade and a worse survival in some tumour types. To assess the prognostic value of EpCAM in urothelial carcinoma of...
pubmedqa
{ "query": "Represent the Biomedical query for retrieving relevant paragraphs:", "pos": "Represent the Biomedical paragraph for retrieval:", "neg": "Represent the Biomedical paragraph for retrieval:" }
Injury and poisoning mortality among young men--are there any common factors amenable to prevention?
[ "Deaths from injury and poisoning (suicide, accidents, undetermined deaths, and homicide) are the major cause of death among young men aged 15-39 years in England and Wales and have been increasing in recent years.AIM: To describe common characteristics among young men who die from injury and poisoning. We employed...
[ "Even though the prevalence of tobacco smoking has declined in the general population and among white-collar workers, the prevalence of tobacco smoking among blue-collar workers remains unacceptably high. Blue-collar workers experience greater exposure to workplace toxins which can add to, or even multiply, their r...
pubmedqa
{ "query": "Represent the Biomedical query for retrieving relevant paragraphs:", "pos": "Represent the Biomedical paragraph for retrieval:", "neg": "Represent the Biomedical paragraph for retrieval:" }
Continuation of pregnancy after antenatal corticosteroid administration: opportunity for rescue?
[ "To determine the duration of continuing pregnancy after antenatal corticosteroid (AC) administration and to evaluate the potential opportunity for rescue AC. Retrospective analysis of women at 24-32 weeks' gestation who received AC at one institution. Six hundred ninety-two women received AC. Two hundred forty-sev...
[ "This review should be cited as: Bricker L, Neilson JP. Routine ultrasound in late pregnancy (after 24 weeks gestation) (Cochrane Review). In: The Cochrane Library, Issue 3, 2000. Oxford: Update Software. A substantive amendment to this systematic review was last made on 01 October 1999. Cochrane reviews are regula...
pubmedqa
{ "query": "Represent the Biomedical question for retrieving relevant documents:", "pos": "Represent the Biomedical document for retrieval:", "neg": "Represent the Biomedical document for retrieval:" }
Does either obesity or OSA severity influence the response of autotitrating CPAP machines in very obese subjects?
[ "The pressures delivered by autotitrating continuous positive airways pressure (CPAP) devices not only treat obstructive sleep apnoea (OSA) effectively but also give potentially interesting physiological information about the forces impinging on the pharynx. In earlier work from this unit, we used correlations betw...
[ "Sleep-disordered breathing (SDB) differs between genders in terms of the type, signs, and symptoms of the disease. Partial upper airway obstruction is underdiagnosed and undertreated. In this study, we retrospectively investigated respiratory sleep recordings of 601 women, ending up with 240 women for the final st...
pubmedqa
{ "query": "Represent the Biomedical question for retrieving relevant documents:", "pos": "Represent the Biomedical document for retrieval:", "neg": "Represent the Biomedical document for retrieval:" }
Does the clinical presentation of a prior preterm birth predict risk in a subsequent pregnancy?
[ "The objective of the study was to determine whether risk of recurrent preterm birth differs based on the clinical presentation of a prior spontaneous preterm birth (SPTB): advanced cervical dilatation (ACD), preterm premature rupture of membranes (PPROM), or preterm labor (PTL). This retrospective cohort study inc...
[ "To examine the effect of method of conception on adverse pregnancy outcome after the 11-13 weeks scan. Prospective screening study for adverse obstetric outcomes in women with singleton pregnancies and live fetus with no obvious defects at 11(+0)-13(+6) weeks. The method of conception was recorded as spontaneous, ...
pubmedqa
{ "query": "Represent the Biomedical question for retrieving relevant passages:", "pos": "Represent the Biomedical passage for retrieval:", "neg": "Represent the Biomedical passage for retrieval:" }
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